Renal Impairment

Question 1

Questions to ask in drug induced renal impairment?

Answer 1

1) Is renal impairment suspected to be drug-induced?
2) Which drug(s) are suspected?
3) U&Es and serum creatinine, eGFR?
4) Is renal impairment acute or chronic?
5) Is the patient receiving renal replacement therapy (RRT), if so how often and what type?

Question 2

U&Es and serum creatinine, eGFR?

Answer 2

• Most recent if possible.
• Are they stable or changing?

Question 3

Questions to ask for enquiries about dosage or suitability of a drug in renal impairment

Answer 3

• What is the indication for the drug and have alternatives been considered?
• What drug would normally be used if the pt did not have renal impairment?
• Is the patient currently taking the drug in question?
• What is the pt eGFR and CrCl?