Renal function + intro to urinalysis Flashcards

1
Q

function of cortical nephron

A

removal of waste

reabsorption of nutrients

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2
Q

function of juxtamedullary nephron

A

concentration of urine

reabsorption of substances

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3
Q

3 main processes of urine formation

A

filtration - glomerulus
reabsorption - renal tubular system
secretion - renal tubular system

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4
Q

act as non-selective filter

A

glomerulus

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5
Q

where do hydrostatic pressure happen?

A

efferent arteriole

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6
Q

substances reabsorb by pct via active and passive transport

A

active: glucose, Na+, amino acid
passive: H2O, urea

++ Cl- and K+

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7
Q

renal threshold ranges from __

A

160-180 mg/dL

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8
Q

the level of renal threshold wherein glucose will start to appear in urine

A

> 180 mg/dL

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9
Q

only part of nephron that does not absorb water

A

ASCENDING LH

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10
Q

renal tubule that control the retention of water and where the renal concentration happen

A

Loop of henle

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11
Q

this is where the final concentration of urinary filtrate begins

A

DCT

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12
Q

it regulates the pH by secreting hyrogen

a. PCT
B. DCT
C. LH

A

DCT

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13
Q

DCT is controlled by what hormones?

A

aldosterone

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14
Q

aldosterone ↑ reabsorption of ___ and secretion of ___

A

sodium (Na+)

potassium (K+)

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15
Q

higher ADH = ___ urine concentration = ____ water loss

a. increase
b. decrease

A

higher ADH = ↑ urine concentration = ↓ water loss

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16
Q

the cell in DCT that senses the changes of BP/ renal arterial pressure

A

MACULA DENSA CELLS - in DCT

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17
Q

the cell un afferent arteriole that produce renin in response to changes in plasma NA+ concentration

A

juxtaglomerular cell - in AFFERENT

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18
Q

renal tubule with selective reabsorption

A

PCT

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19
Q

a polymer of fructose

A

INSULIN

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20
Q

reference method but SELDOM the method of choice unlike creatine

A

INSULIN

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21
Q

it is neither reabsorbed nor secreted by tubules

22
Q

1st function affected by renal disease and earlier than GFR

A

loss of tubular reabsorption

23
Q

2 earliest tubular reabsorption test

A

fishberg

mosenthal

24
Q

in this method, patients were deprived of fluid for 24 hrs prior measuring SG

25
this method compares the volume of SG of day and night urine sample
MOSENTHAL
26
this component has no importance to osmolarity
UREA
27
lactic acid will be _____ if serum sample are not separated or refrigerated within a. not affected b. falsely increased c. falsely decreased
FALSELY INCREASED (both FP & VP)
28
effect of ethanol to vapor pressure a. not affected b. falsely increased c. falsely decreased
not affected
29
effect of ethanol to freezing point a. not affected b. increased c. decreased
increased
30
What are the major inorganic dissolved solid?
Chloride (Cl-) Sodium (Na+) Potassium (K+)
31
major organic components are:
urea creatinine uric acid
32
majority of the total dissolved solids in urine is the ___
urea (primary organic component)
33
an organic component which commonly seen in kidney stone and is derived from catabolism of nucleic acid
uric acid
34
an organic component that is associated with high-vegetable diets
hippuric acid
35
what are the other inorganic components combined with POTASSIUM
chloride, sulfide, phosphate, salt
36
Inorganic compound derived from glutamine in kidneys and metabolism of protein
AMMONIUM
37
In 1627, he wrote a book about charlatans (pisse prophets) which inspired the passing of the first medical licensure law in England
Thomas Bryant
38
Who discovered albuminuria by boiling urine
Frederik Dekker (1694)
39
Timed collection for addis count
12-hour collection
40
Timed collection for nitrite determination
4-hour collection
41
24 hour collection is for A. Urobilinogen B. Quantitative Chemical tests C.Nitrite determination D. Addis count
B. Quantitative Chemical tests
42
Type of urine optimum for preservation of casts and cells
FIRST MORNING
43
Most concentrated and most acidic type of specimen
FIRST MORNING
44
Afternoon specimen is for detection of ___
Urobilinogen
45
Affected analyte when there are Bacterial growth and precipitation of amorphous material
CLARITY
46
Affected analyte when there are Volatilization and bacterial metabolism
KETONE
47
How many hour does refrigeration prevent bacterial growth
24 hours
48
It Preserves glucose and sediments well
Thymol
49
Is bacteriostatic at 18 g/L; can be used for culture transports
Boric acid
50
An excellent sediment preservative
FORMALIN
51
Preservative that may be used instead of reagent sodium fluoride
Sodium benzoate
52
It does not interfere routine test but can change odor
Phenol