Renal Formulas Flashcards
1
Q
GFR
A
- = Kf x NFP
- = (U inulin x V) / (P inulin)
(ml/min)
2
Q
Excretion rate
A
= V x U
V - urine excretion rate
U - urine concentration of compound
(mg/min, mmol/min, mEq/min)
3
Q
Urine concentration of compound (U)
A
= plasma concentration x GFR
4
Q
Ohms law
A
Delta P = GFR x vascular resistance
5
Q
Clearance
A
= (V x U) / plasma concentration
(ml/min)
6
Q
Filtration fraction
A
= GFR / renal plasma flow
7
Q
Renal plasma flow
A
- = renal blood flow x (1-HCT)
- = (U pah x V) / (arterial pah x venous pah)
(ml/min)
8
Q
Clearance ratio
A
= Cs / C inulin
(No units)
9
Q
Renal blood flow
A
- = RPF / (1-HCT)
- = delta P (renal art - renal vein) / total vascular resistance
(ml/min)
10
Q
Reabsorption rate
A
- = filtered load - excretion rate
- = (GFR x Ps) - (Us x V)
(mg/min, mmol/min, mEq/min)
11
Q
Secretion rate
A
= excretion rate - filtered load
(mg/min, mmol/min, mEq/min)
12
Q
Filtered load
A
= GFR x plasma concentration
13
Q
OAT
A
- anions (-)
- Na+ dependent
- basolateral side:
1) symport: 3 Na+ with 1 a-KG
2) Na/K/ATPase pump
3) antiport: 1 anion in and 1 a-KG out - luminal:
1) anion into lumen
14
Q
OCT
A
- cations (+)
- H+ dependent
- basolateral side:
1) Na/K/ATPase pump
2) uniport: cation in (inside of cell is -) - luminal:
1) antiport: 1 H+ in, C+ out
15
Q
Endogenous OAT (7)
A
- bile salts
- fatty acids
- hydroxybenzoate
- hippurate (PAH)
- oxalate
- urate (uric acid)
- prostaglandins
