Renal Final Clicker Q's Flashcards

1
Q

Juxtamedullary nephrons are distinct from cortical nephrons in that they

A

Have significantly longer loop of Henle (and descent deeper into the medulla)

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2
Q

Name the muscle responsible for contraction of the bladder:

A

Detrusor

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3
Q

When a patient is in standing position, approximately where should the kidneys be located?

A

Between L1 and L4

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4
Q

The bladder is innervated by the ___ nerve cord segments?

A

S2 and S3

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5
Q

The externa sphincter is controlled by the _____ nerve

A

Pudendal

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6
Q

What starts the micturition reflex?

A

Sensory stretch receptors in the bladder wall

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7
Q

Water will move across a selectively permeable membrane from a region of ____ water concentration to a region that has a ____ water concentration

A

HIGH to LOW

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8
Q

The most variable source of water lost from the human body is water lost via:

A

Urine (water excreted via kidneys)

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9
Q

The membranes of the glomerulus carry a negative charge to help prevent the passage of:

A

Proteins

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10
Q

How many layers are present at the glomerular capillary membrane?

A

3

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11
Q

How are the capillaries of nephrons different from others in the body?

A

They are three layers of material (instead of 2)

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12
Q

Which of the following is the correct equation for calculating the filtration fraction?

A

FF=GRF/RPF

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13
Q

Colloid osmotic pressure in the glomerulus is proportional to the concentration of:

A

Proteins in the bloodstream

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14
Q

Tubular reabsorption is *Glomerular filtration is non-selective

A

Highly selective

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15
Q

In the proximal tubule, reabsorption of sodium from filtrate into the tubular cells uses

A

Diffusion

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16
Q

Proteins and amino acids are reabsorbed from the filtrate via:

A

Pinocytosis

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17
Q

The limit to the rate at which a solute can be transported during active reabsorption or secretion is the:

A

Transport maximum

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18
Q

Which portion of the loop of henle is impermeable to water?

A

Thick ascending

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19
Q

In which portion ff the loop of henle do we see significant active transport of sodium?

A

Thick ascending

20
Q

How has the osmolatiry of filtrate changed when it reaches the end of the proximal tubule?

A

It has stayed the same

21
Q

What will happen to reabsorption rates if we raise peritubular capillary hydrostatic pressure in the kidneys?

A

Decrease

22
Q

What is the primary function of ADH (vasopressin)?

A

Help the body retain water

23
Q

How has the osmolarity of the filtrate changed from initial formation to when it reaches the bottom of the loop of henle?

A

Increased

24
Q

___ may be recycled many times between the medulla tissue and the filtrate in the renal tubule?

A

Urea

25
Q

Besides color, what is one clinical test that could be performed to determine urine concentration levels?

A

Urine specific gravity

26
Q

Which of the following is NOT a systemic change the body uses to maintain extracellular fluid balance?

A

Change fluid intake

27
Q

An increase in blood pressure leading to an increase in the volume of urine excretion is called?

A

Pressure diuresis

28
Q

A person who is salt-sensitive sees a _____ increase in blood pressure with ____ salt intake?

A

Large increase in BP with very little salt intake

29
Q

Increasing the levels of ADH in your bloodstream will lead to _____ reabsorption of water in the kidneys?

A

Increased

30
Q

When you have leakage of fluid from the circulatory system into extracellular spaces, the kidneys will react by____?

A

Reabsorbing additional water

31
Q

The majority (~65%) of potassium reabsorption in the kidneys occurs in the ______?

A

Proximal tubule

32
Q

When there is potassium depletion in the body, there will be additional potassium reabsorption in the ______?

A

Intercalated cells

33
Q

Acute acidosis will result in ____ potassium secretion and chronic acidosis will result in _______ potassium secretion?

A

Acute= decreased K+ secretion, chronic= increased K+ secretion

34
Q

Approximately how much of the calcium filtered at the glomerulus is reabsorbed by the kidneys?

A

99%

35
Q

Magnesium removal from the blood stream occurs primarily at the:

A

Glomerular capsule

36
Q

The majority of phosphate reabsorption in the kidneys occurs in the:

A

Proximal tubule

37
Q

If a person’s blood pH drops below 7.4 they have:

A

Acidosis

38
Q

Most HCO3 reabsorption occurs in the______?

A

Proximal tubule

39
Q

Primary active transport of H+ occurs in the ________ cells

A

Intercalated cells

40
Q

The primary amino acid used for gluconeogenesis in the kidneys is_____?

A

Glutamine

41
Q

Regardless of the type, diuretics act on the nephrons of the kidneys to_____?

A

Increase urine volume output

42
Q

Hyponatremia can be dangerous because it can cause cells to_____?

A

Swell

43
Q

A key distinction between nephrotic and nephritic syndrome is the presence of ____ in the urine in a person with nephritic syndrome

A

Nephritic= blood (also has proteins but blood is specific to nephritic)

44
Q

If left untreated, cystitis could result in_______?

A

Polycystic kidney disease

45
Q

Polycystic kidney disease (PKD) is entirely a _____ disease

A

Genetic

46
Q

The purpose of dialysis is to

A

Replace kidney function

47
Q

Currently, the most common case of chronic kidney disease is:

A

Diabetes