Renal dysfunction Flashcards

1
Q

Describe the mechanism by which NSAIDs are nephrotoxic

A

NSAIDs inhibit prostaglandin synthesis, leading to vasoconstriction and reduced renal perfusion

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2
Q

Describe the mechanism by which gentamicin is nephrotoxic

A

Directly nephrotoxic - gentamicin causes acute tubular necrosis

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