Renal Disorders Flashcards
Acute Kidney Injury/Acute Renal Failure
- occurs suddenly/generally reversible
- abrupt loss of kidney function and glomerular filtration rate
Glomerular Filtration Rate (GFR)
test used to check how well the kidney’s are working; estimates how much blood passes through the glomeruli each minute
Glomeruli
cluster of capillaries around end of kidney’s where waste products are filtered from blood
Causes of Acute Kidney Injury Prerenal
- diabetes
- fluid volume deficit; GI, hemorrhage, diuretics
- decreased cardiac output; MI, CHF
- prolonged hypovolemic status; sepsis, anaphylaxis, antihypertensive
AKI Prerenal
blood flow INTO kidney is affected
AKI Intrarenal
damage to the actual kidney
AKI Intrarenal Causes
- rhabdomyolysis
- nephrotoxicity; mycin antibiotics, IV dye, ACE inhib, NSAIDS
- infections; pyelonephritis
AKI Postrenal Causes
- bilateral kidney stones
- tumors
- BPH
- ureteral strictures
AKI Postrenal
flow of urine OUT of kidney is affected
How many phases of AKI are there?
4
Phase 1 AKI (onset)
triggering event begins—start of kidney injury
Phase 2 AKI (oliguric)
- urine output decreases and fluid volume overload develops
- serum waste begins to increase (BUN, Cr, K+, Mg+, Phosphorus)
Phase 3 AKI (diuretic)
- triggering event is corrected
- urine output increases, sometimes in in large dilute amounts
Phase 4 AKI (recovery)
- kidney function improves
- health status improves/energy increases
S/S of AKI
- Oliguria
- Anuria
- low specific gravity
- hyperkalemia
- metabolic acidosis
- increased BUN/Creatinine
- hypocalcemia/hyperphosphatemia
Oliguria
< 400 mL in 24 hrs
Anuria
< 50 mL in 24 hrs
Hyperkalemia w/ AKI
- cardiac arrhythmias w/ EKG changes
- tall peaked T-waves
- muscle weakness/paralysis
- nausea/diarrhea
- decreased or absent DTR’s
Hypocalcemia w/ AKI
- tetany
- seizures
- prolonged QT interval on EKG
- trousseau sign
- Chvostek sign
Trousseau Sign
carpal spasm that is the result of inflation of a BP cuff
Chvostek Sign
twitching of facial muscles in response to tapping over the area of facial nerve
Prevention of AKI
- prevent dehydration
- replace blood and fluids as appropriate
- strict I&O’s
- Assess BUN & Creatinine routinely on patients at risk
- Do NOT give IV contrast w/ elevated creatinine
- treat infections quickly
- eliminate use of catheters
- prompt perineal care
- assess use of nephrotoxic drugs
Treatment for Prerenal AKI
IV fluids / blood transfusions
Treatment for Intrarenal AKI
temporary dialysis
-prevent FVE, hyperkalemia, metabolic acidosis
Treatment for Postrenal AKI
remove obstruction
- prostatectomy
- stents
- indwelling catheter
Complications of Fluid Volume Excess
- hypertension
- congestive heart failure
- pericarditis
- pulmonary edema