Renal Cancer Flashcards
1
Q
What are the components of Culp criteriae ?
A
Low albumin, high LDH, T3 or T4, Primary tumor, symptomatic metastasis, liver metastasis, lymph node metastasis
2
Q
What are the variables for Heng Criteriea for metastatic rcc?
A
Hgb Neutrophils calcium platelets performance status(karnofsky) Time to systemic therapy from diagnosis
3
Q
what are the different classifications and what do they mean for Heng Criteriea?
A
0: 43 months OS
1-2 23m OS
>3 8m OS
4
Q
What are the component of Motzer?
A
Hgb LDH platelets performance status(karnofsky) Time to systemic therapy from diagnosis
5
Q
What is the meaning of different classes of motzer and what do they mean?
A
0: Median OS 20 months
1-2: 10 months
3 4 months
6
Q
Name 7 different genetic disorders associated with familial RCC?
A
1- Tuberous sclerosis 2- Birt Hogg dube 3- Von hippel lindau 4-PTEN heamrtoma syndrome/ cowden syndrome 5- Hereditary papillary RCC 6- Hereditary leiomiotosis and RCC 7-Succinate dehydrogenase associated RCC others: Li-fraumani syndrome BAP1 hereditary cancer syndrome
7
Q
What is culp criteriae used for?
A
to determine who is less likely to benefit from cytoreductive nephrectomy
