renal anat Flashcards
what is the mesonephric duct also known as?
Wolffian duct
what is the paramesonephric duct also known as?
Mullerian duct
what does the allantois give rise to?
bladder
what is the collecting duct derived from?
ureteric bud
what is the nephron derived from?
metanephrogenic mesenchyme
what mesoderm is the kidney derived from?
intermediate mesoderm
what structures does the mesonephric duct mainly give rise to?
male reproductive structures (testes, ductus deferens, seminal vesicles)
what structures does the paramesonephric duct mainly give rise to?
female reproductive structures (fallopian tubes, uterus, proximal vagina)
what does the ureteric bud form?
drainage components of urinary system: collecting ducts, renal calyces, renal pelvis, ureters
what does the metanephric mesenchyme form?
nephrons (glomerulus, PCT, LoH, DCT) and interstitium
what are the 6 stages of nephrogenesis?
- mesenchymal cell condensation (aggregation)
- epithelial vesicle
- comma-shaped body
- s-shaped body
- capillary loop stage glomerulus
- maturing glomerulus
what the 3 muscles of posterior abdominal wall (medial to lateral)?
psoas major, quadratus lumborum, iliacus
describe the median arcuate ligament anatomically
surrounds aortic hiatus, connects diaphragmatic crura
describe the medial arcuate ligament anatomically
arches over psoas major and sympathetic trunks
thickening of psoas fascia curving from L1 vertebral body to transverse process
describe the lateral arcuate ligament anatomically
arches over quadratus lumborum and subcostal nerves and vessels
thickening of lumbar fascia from L1 transverse process to 12th rib
nerve roots of iliohypogastric nerve and relation to psoas major
T12-L1
runs under psoas major and emerges at its lateral border to run over quadratus lumborum
nerve roots of ilioinguinal nerve
L1
nerve roots of genitofemoral nerve and relation to psoas major
L1-L2
pierces psoas at L3/4 emerging on its anterior surface
nerve roots of lateral femoral cutaneous nerve and it’s relation to psoas major
L2-3
lateral border of psoas major
nerve root of femoral nerve and relation to psoas major
L2-4
lateral border of psoas major
nerve roots of obturator nerve and relation to psoas major
L2-4
medial border of psoas major
boundaries of lumbar triangle (anterior, posterior and inferior)
anterior: external oblique muscle
posterior: latissimus dorsi
inferior: iliac crest
what is the T8 hiatus and what structures run through it)
caval hiatus
IVC, right phrenic nerve, lymphatics
what is the T10 hiatus and what structures run through it)
oesophageal hiatus
oesophagus, anterior and posterior vagal trunks
what is the T12 hiatus and what structures run through it?
aortic hiatus
aorta, thoracic duct, azygos vein
what vertebral level is kidneys?
right: L1-4
left: T12-L3
arrange these structures from anterior to posterior
1. renal artery
2. renal pelvis
3. renal vein
4. splenic vein
splenic vein, renal vein, renal artery, renal pelvis
which renal vein is longer?
left renal vein
which renal artery is longer?
right renal artery
which renal vein runs posterior to SMA?
left renal vein
which renal artery runs posterior to IVC?
right renal artery
blood flow in kidney from renal artery to peritubular capillaries
renal artery –> segmental –> interlobar –> arcuate –> interlobular –> afferent arterioles –> glomerulus –> efferent arterioles –> peritubular capillaries
order of veins from vasa recta to renal vein
vasa recta –> interlobular –> arcuate –> interlobar –> renal vein
what is the lymphatic drainage of kidneys?
para-aortic LN –> cisterna chyli
what is the lymphatic drainage of paired viscera?
para-aortic/lumbar LN
what is the lymphatic drainage of unpaired viscera?
pre-aortic LN
what are the four layers surrounding the kidney? (superficial to deep)
- pararenal fat
- renal/Gerota’s fascia
- perirenal fat
- renal capsule
what are the two types of nephrons?
cortical and juxtamedullary nephron
which nephron has a longer LoH?
juxtamedullary nephron
which nephron has its glomeruli in the outer cortex?
cortical nephron
what are the 3 resident cell types in the glomerulus?
- endothelial cell
- mesangial cell
- podocytes
which part of the nephron does extensive ion exchange occur?
distal convoluted tubule
which part of the nephron plays a major role in absorption of tubular contents?
proximal convoluted tubule
what type of epithelium lines the collecting ducts?
simple cuboidal
what type of epithelium lines the distal tubules?
simple cuboidal
what type of epithelium lines the proximal tubules?
simple columnar or cuboidal
where is renin synthesised?
juxtaglomerular cells which is part of the juxtaglomerular apparatus
what are the 3 parts of the JGA?
- macula densa
- extraglomerular mesangium (lacis cells)
- juxtaglomerular cell
what type of epithelium lines the ureters?
transitional epithelium/urothelium
which part of the ureter has thick lamina propria and thin muscularia externa?
proximal ureter
which part of the ureter has thin lamina propria and thick muscularis externa?
distal ureter
what structures do the ureters pass under?
uterine artery/vas deferens
what are the 3 typical sites of constriction of ureter?
- ureteropelvic junction (UPJ)
- pelvic brim (where ureter crosses anterior to common iliac artery at L5)
- ureterovesical junction
what is the arterial supply of the upper ureter?
renal artery
what is the arterial supply of the middle ureter?
aorta, gonadal artery, common iliac a.
what is the arterial supply of the lower ureter?
internal iliac a.
what type of epithelium lines the bladder?
stratified transitional epithelium (stratified columnar –> squamous)
where are the transient receptor potential (TRP) receptors found?
lamina propria of bladder wall
what are the 3 layers of muscle of detrusor muscle?
longitudinal, circular, longitudinal
which adrenal gland is pyramidal?
right adrenal gland
which adrenal gland is crescenteric?
left adrenal gland
what are the 3 layers of adrenal cortex?
- zona glomerulosa
- zona fasiculata
- zona reticularis
which vein does the left suprarenal vein drain into?
left renal vein
what does the right suprarenal vein drain into?
IVC
which artery does the superior suprarenal artery branch from?
inferior phrenic artery
where does the middle suprarenal artery branch from?
abdominal aorta
which muscle is most likely to be injured in punctured kidney?
quadratus lumborum
where is ureteric pain referred to and what nerve fibres carry them?
loin to groin
SNS afferents
which glomerular filtration layer prevents the leakage of red blood cells?
fenestrated endothelium
which nerve is responsible for the cremaster reflex?
ilioinguinal nerve
what processes does Bone Morphogenetic Protein 4 (BMP4) inhibit?
ureteric budding and branching morphogenesis
by the end of week ___, the pronephros disappears and does not function
week 4
in horseshoe kidney, the kidneys are trapped under ___
IMA
The sympathetic nerves that supply the bladder originate from:
a. T1-3
b. T4-6
c. T10-L2
d. T8-9
c. T10-L2