Renal Flashcards
Calcinuerin inhibitors
- cyclosporine
- tacrolimus
Cyclosporin:
Hypertension; decreased GFR; dyslipidemia; hirsutism
Tacrolimus:
New-onset diabetes mellitus; decreased GFR; hypertension; gastrointestinal symptoms
Antimetabolite, blocker of de novo purine synthesis
- Mycophenolate
- azithoprine
Mycophenalate: Diarrhea; nausea/vomiting; leukopenia; anemia
Azithoprine: leukopenia
mtor
sirolimus
Proteinuria; dyslipidemia; new-onset diabetes mellitus; anemia; leukopenia
BPH
- Diagnosis
- Management
Diagnose:
- — LUTS sx
- — UA
- — Do not do a PSA
- — Exam: prostate smooth, enlarged. If nodular, indurated or asymmetric consider adenocarcinoma
Treatment:
- – UAU score < 8- conservative measures
- – UAU >/= 8 Pharmacologic measures
- —- alpha blockers
- —- Finasteride (only if prostate >40)
Polycystic Kidney Disease
- Diagnosis
- Treatment
- Associated syndromes
Diagnosis: Proteinuria, hematuria, HTN, Bilateral Masses
Treatment: Treat HTN
Associated Syndromes:
- pancreatic and hepatic cysts
- diverticulosis
- intracranial aneurysm (SAH)
- Aortic valve disease and aortic root disease
Who to Screen for Aneurysms in APCKD
- Family hx of rupture
- Personal hx of rupture
- High risk profession
Screen with time of flight MRI
AIN
Febrile
Rash
Eosinophilia
Eosinophiluria
Sterile pyuria with WBC casts
Hematuria
Eos
Biopsy (not required) inflammatory infiltrate, Edema
Treatment:
- remove offending agent (PPI, NSAID, antibiotics etc. )
- If does not improve may require Glucocorticoids
CKD electrolyte (P and Ca goals)
PTH <300
Phos 3.5-5.5
Ca 8.4-9.5
CaxP product <55