Renal

Question 1

First pathophysiological change in DM nephropathy

Answer 1

Hyperfiltration
Followed by:
GBM thickening,
Mesangial expansion,
Proteinuria,
Renal tubular injury (proximal)
Progression to CKD and ESRF

Question 2

Which immune cells involved in renal allograft rejection (acute cellular rejection)

Answer 2

T cells

Question 3

Which Immune cells involved in ab mediated rejection of renal allograft?

Answer 3

B cells

Question 4

Types of transplant rejection

Answer 4

Acute cellular rejection - rare
Ab mediated rejection

Question 5

IgA nephropathy is the most common cause of glomerulonephritis, how does it normally present?

Answer 5

Haematuria