Renal

Question 1

First line Mx for pyelonephritis

Answer 1

Cefalexin or co-amoxiclav for 7-10 days

Question 2

First line mx for UTI

Answer 2

Trimethoprim or Nitrofurantoin

Question 3

What increases the risk of AKI with contrast agents?

Answer 3

Being aged 75 or over

Question 4

What medication can increase serum creatinine and why?

Answer 4

Trimethoprim competitively inhibits the mechanism for tubular secretion of creatinine through the base-secreting pathway, leading to an increase in serum creatinine.

Question 5

What would you give a patient with pyelonephritis who also has a penicilin allergy?

Answer 5

Ciprofloxacin as cefalexin is structurally similar to penicilin

Question 6

What abx do you give to female with UTI coming to term?

Answer 6

Cefalexin

Question 7

What does long term use of nitrofurantoin lead to?

Answer 7

Restrictive lung disease

Question 8

When should you avoid the use of nitrofuratoin in UTI?

Answer 8

If GFR is <45
Use Trimethoprim

Question 9

If asymptomatic women comes in with urine dipstick showing neutrophils and nitrites, what to do?

Answer 9

Prescribe Cefalexin as asymptomatic bacteriuria is possible during pregnancy