Renal

Question 1

autosomal dominant politic kidney disease is most commonly caused by an abnormality on which chromosome

Answer 1

16

Question 2

What are some non cystic manifestations of ADPKD?

Answer 2

Mitral valve prolapse, intracranial berry aneurysms, colon diverticula, renal cell carcinoma

Question 3

Spot diagnosis: hametauria, flank pain, HTN, stroke, renal failure, palpable masses, UTIS

Answer 3

ADPKD

Question 4

Definition of fanconi syndrome

Answer 4

Inherited/ acquired disorder of renal tubular transport

Question 5

Door diagnosis: Pollution, polydipsia, dehydration, rickets/ osteomalacia

Answer 5

Fanconi syndrome

Question 6

Define nephrocalcinosis

Answer 6

Parenchymal calcium deposition in kidney usually 2 hypercalcaemia

Question 7

Timeline of IgA nephropathy (Bergers disease)

Answer 7

24-48 hours after URTI

Question 8

How does IgA nephropathy present

Answer 8

Nephritic syndrome (visible haematuria)
24-48 hours after URTI

Question 9

Presentation of post-streptococcal glomerulonephritis

Answer 9

2 weeks after infection with nephrotic syndrome
Haematuria, oliguria, oedema)

Question 10

Management of IgA nephropathy
Prognosis?

Answer 10

High dose pred can reduce proteinuria and delay renal impairment
Immunosuppressive drugs if deteriorating
20-30% end up with end stage renal failure

Question 11

Treatments for diabetes insipidus

Answer 11

Desmopressin
Thiazide Diuretics
NSAIDS
Sodium restriction

Question 12

Difference between cranial and nephrogenic diabetes insipidus

Answer 12

Cranial- deficiency in ADH
Nephrogenic- insensitivity of kidneys to ADH

Question 13

Goodpastures syndrome triad

Answer 13

1. Pulmonary haemorrhage
2. Glomerulonephritis
3. Anti GBM antibodies