Renal Flashcards
Acute Glomerulonephritis
* Symptoms
* Causes
Symptoms:
* Hematuria – leads to cola-colored urine
* Proteinuria
Causes:
* Group A beta-hemolytic streptococcal infection of the throat may proceed glomerulonephritis by 2-3 weeks
* Repeated episodes of acute nephritic syndrome
What is acute glomerulonephritis?
Inflammation of glomeruli (filters in the kidneys)
When does acute glomerulonephritis usually occur?
2-3 weeks after a strep infection
List the GFR for each stage of Chronic Kidney Disease
Stage 1:
* GFR >/= 90
Stage 2:
* GFR = 60-89
Stage 3:
* GFR = 30 - 59
Stage 4:
* GFR = 15-29
Stage 5:
* GFR > 15
What are the 3 types of acute renal failure / acute kidney injury (AKI)?
1.) Pre-renal
2.) Intrinsic
3.) Post-renal
What 3 key factors increase a patient’s risk of chronic kidney disease?
- AGING
- Heart failure (& HTN)
- Contrast
What should be done to prevent kidney damage due to contrast in patients with AKI or CKD?
Pre-procedure hydration
What is Grey-Turner’s Sign and what does it indicate?
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purplish discoloration on the flank or near 11th / 12th rib
- indicates retroperitoneal bleed / kidney injury
What is Grey-Turner’s Sign?
Purplish discoloration on the flank or near 11th / 12th rib
What does Grey-Turner’s sign indicate?
Sign of kidney injury
What is normal Creatinine?
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0.6 - 1.2 mg/dL
What is normal blood urea nitrogen?
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8 - 20 mg/dL
What kind of disease is polycystic kidney disease & what can it lead to?
- Genetic disorder (autosomal dominant)
- Can lead to kidney failure
What is the main sign of acute renal failure (/ AKI)?
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Oliguria = < 300 mL / 24 hr of urine
What is acute renal failure (ARF) / acute kidney injury (AKI)?
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RAPID decline (over hours to days) in GFR
* leads to rapid ↑ in BUN & ↑ creatinine, & possibly ↓ urine output
What is the treatment for acute renal failure (ARF) / acute kidney injury (AKI)?
- Give fluid
- Treat electrolyte imbalance
What is nephrotic syndrome?
- Excess fluid volume
- Generalized edema
- body excretes too much protein in the urine (proteinuria)
What is acute tubular necrosis?
destruction / death of tubules in the kidneys
What are causes of acute tubular necrosis (ATN)?
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- Nephrotoxic medications
- Environmental exposures
- Sepsis
- Prolonged severe HTN
What type / classification of kidney injury is acute tubular necrosis (ATN)?
Acute Kidney Injury (AKI) – intrinsic
* within the kidney)
What are the stages of acute tubular necrosis (ATN)?
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1.) Onset phase: lasts hours to days
2.) Oliguric / Anuric Phase: 5-16 days
* nectrotic cellular debris blocks urine & damage is done to the tubular wall
3.) Diuretic Phase: 7 - 14 days
* ↑ GFR & polyuria
* Monitor for dehydration
4.) Recovery / Convalescent Phase
* even more ↑ in urine output
* BUN & creatinine either ↑ or stay at their new normal
What is the treatment for hyperkalemia?
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- Glucose (hypertonic)
- Insulin infusion
- Calcium
- Kayexalate can also be given – it will bind K+ in the bowel & eliminate K+ in the feces
What is the treatment for a creatinine level over 2?
Acetylcysteine
* make sure pt is hydrated before CT contrast is administered
What can hyperkalemia lead to?
- Peaked T-waves
- Widening QRS
- may cause V-tach