Renal Flashcards
What is the primary function of the renal and urinary system?
homeostasis
kidney’s specific role in homeostasis
regulating fluid and electrolytes, removing wastes, and providing hormones that are involved in red blood cell (RBC) production, bone metabolism, and blood pressure.
each kidney has how many nephrons
1 million
purpose of nephrons
filters blood
purpose of the glomerulus
filtration of waste
what can alter filtration
Increases in the glomerular capillary hydrostatic pressure cause increases in net filtration pressure and GFR
increases in Bowman space hydrostatic pressure causes decreases in filtration pressure and GFR
a substance moves from the filtrate back into the peritubular capillaries or vasa recta
tubular reabsorption
a substance moves from the peritubular capillaries or vasa recta into tubular filtrate
tubular secretions
What are some substances that should not be found in urine and why?
no protein = damage happens quickly to kidneys
no glucose in urine = diabetes
blood = internal bleeding
measuring the ratio of the amount of solutes (milliosmoles) to water using liters
osmolarity
calculates the ratio of the amount of solutes (milliosmoles) to water using weight or kilograms
osmolality
percentage of K filtered through the kidneys
90%
how is water regulated by kidneys
ADH/vasopressin
volume of electrolytes excreted each day by the kidneys
excretion is equal to intake per day
regulation of acid base balance by the kidneys
filtering bicarbonate and phosphate
results in metabolic acidosis
vessels constantly monitor blood pressure as blood begins its passage into the kidney
vasa recta
specialized juxtaglomerular cells near the afferent arteriole, distal tubule, and efferent arteriole secrete the hormone:
renin
Why is (MAP- Mean arterial pressure) important?
MAP of 65 maintains renal perfusion
how do kidneys regulate RBCs
releasing erythropoietin - which stimulates bone marrow to produce RBCs
purpose fo regulation of Vit D
production of calcium from active form of Vit D
purpose of prostaglandins
vasodilatory effects and important in maintaining renal blood flow
kidneys function of regulating waste
kidney is main excretory organ, eliminating body’s metabolic waste product
assessment involved for renal/urinary tract
Health History
Social History
Recognize cues (subjective data)
Costovertebral angle
labs for renal/urinary tract
Urinalysis and Urine Culture
Renal clearance
Creatinine clearance
Creatinine level (0.6- 1.2)
BUN (7-20)
GFR 120- 130mL/min
diagnostics for renal
Imagining
Ultrasounds
Urologic Endoscopic
Bladder Scan
what is post void residual
amount of urine left in bladder after urinating
what do we want a PVR to be
less than 50
less than 350
progressive loss of kidney (nephron) function
kidney disease 1
percentage of those with CKD that do not know
70%
nephron level classification for kidney disease
nephron functioning less than 20%
risk factors for kidney disease
diabetes and HTN
proteinuria
greater than 60 YO
family history
GFR indication for end stage renal disease
less than 15
clinical manifestations of CKD
hypertension
heart failure
hyperkalemia
metabolic acidosis
pulmonary edema
edema
uremia
GI and neuro symptoms
anemia
skeletal buffering
hypocalcemia
hyperphosphatemia
hyperparathyroidism
osteodystrophies
diagnostic testing for CKD
Lab work/ Urine Studies
K+ - hyperkalemia
Creatinine clearence – excreted in urine
Creatine level – 0.6-1.2
Hgb
BUN (7-20)
Magnesium
GFR – 120-130
Renal Ultrasound
Renal Biopsy –risk for bleeding
CT scan
medicatoins for CKD treatment
Sodium Polystyrene (Kayexalate) - Patiromoer (Veltassa) – decrease K
ACE Inhibitors and ARBs –lower BP
Svelamer carbonate (Renvela) - Calcium Acetate (PhosLo) – lowers phosphate
Calcium and Vit D – supplementation
Cinacalcet (Sensipar)
Exogenous Erythropoietin - Epogen, Procrit
Iron – reproduce RBC
Statins (Atorvastatin-Lipitor)
Gemfibrozil (Lopid) -cholesterol – build up – stops blockages
medications for CKD to decrease potassium
Sodium Polystyrene (Kayexalate)
Patiromoer (Veltassa)
medications for CKD to lower BP
ACE inhibitors
ARBs
medications for CKD to lower phsophate
Svelamer carbonate (Renvela)
Calcium Acetate (PhosLo)
medications for CKD to supplement
calcium
Vit D
medications for CKD to treat hyperparathyroidism
Cinacalcet (Sensipar)
medications for CKD to reproduce RBCs
Exogenous Erythropoietin
Epogen
Procrit
Iron
medications for CKD to lower cholesterol building and stop blockages
Statins (Atorvastatin-Lipitor)
Gemfibrozil (Lopid)
nutrition restrictions for CKD
protein restriction
fluid restriction
sodium restriction
potassium restriction
phosphate restriction
why do we restrict protein for patients with kidney disease and how do we monitor
causing damage and increases toxins
monitor lab work
why do we restrict fluid for patients with kidney disease and how do we monitor
avoid fluid overload
based on urine output
why do we restrict sodium for patients with kidney disease and how do we monitor
hurt kidneys cannot filter and control with ADH
2-4 grams/day
why do we restrict potassium for patients with kidney disease and how do we monitor
kidneys responsible for filter of 90% of potassium
2000-3000mg
monitor lab work
why do we restrict phosphate for patients with kidney disease and how do we monitor
hyperphosphatemia
1g/day
limit meat and dairy products
purpose of renal replacement therapy
diffusion, osmosis, ultrafiltration
remove waste
filters blood
vascular access for hemodialysis
Temporary Vascular Access
Arteriovenous fistula (AVF) – A
Arteriovenous graft (AVGs) – B – IV drug users – scar tissue
how to assess fistula
feel thrill
listen to bruit
assessment of vascular assess sites
Assess for maintenance
Assess for infection
Assess for possible obstruction
frequency and length of hemodialysis
Completed on average 3 times per week for 3-4 hours
what medications the nurse should hold before dialysis
cardiac glycosides
antibiotic agents
antiarrythmic medications
antihypertensive agents
blood products
blood thinners
complications of hemodialysis and what causes thme
dysrhythmias - too much potassium and fluid
chest pain - potassium - fluid shift - hemoglobin
hypotension - fluid/blood loss
muscle cramps - hyperkalemia
hepatitis - sterility
process of PD
infuse 2 L of fluid
allows both diffusion and osmosis to occur
drainage portion of the exchange begins
The solution drains from the peritoneal cavity by gravity through a closed, sterile system. Usually drainage is completed in 10 to 30 minutes.
peritoneal dialysis access
Tenckhoff Catheter
Inserted through abdominal wall.
Takes 2 weeks to heal.
Can be used immediately with low volume of fluid.
Monitor for signs of infection
complications for PD
exit site infection
peritonitis
hernias and lower back problems
bleeding
pulmonary complications
protein loss
assessment for PD access
H&P
Complete history of any existing kidney disease, family history
Long-term health problems
Drugs and herbal preparations
Dietary habits
Support systems
Output
Skin – itching and edema
Chest pain or palpitations
nursing diagnoses for kidney disease
Excess fluid volume
Risk for electrolyte imbalance
Risk for injury
Anemia
Imbalanced nutrition: less than body requirements
overall planning goals for kidney disease
Demonstrate knowledge and ability to comply with therapeutic regimen
Participate in decision making
Maintain normal fluid volume status
Preserve kidney function
Minimize complications
health promotion fro kidney disease
Identify individuals at risk for CKD
Diabetes mellitus
Hypertension
History or family history of kidney disease
Repeated urinary tract infection
Regular checkups and changes in urinary appearance, frequency, and volume should be reported
acute care for CKD
Most care for CKD occurs on an outpatient basis
In-hospital care required for management of complications and for kidney transplantation
ambulatory care for CKD
Patient can complete evaluation for kidney transplant
Explain what is involved in PD or HD, home dialysis modalities, transplantation, palliative care
Teach patient and caregiver about
Diet
Drugs
Common side effects
Pill organizer
Avoid over-the-counter drugs
Take daily BP
Identify signs of fluid overload, electrolyte imbalances
evaluation for CKD
The patient with CKD will maintain:
Fluid and electrolyte levels within normal ranges
Absence of complications
An acceptable weight with no more than a 10% weight loss
Adherence to treatment plan
possible complications for upper urinary tract infections
sepsis
UTI
normal defense to prevent UTIs
urinating
acidic PH
high urea concentration
glycoproteins
classification of UTIs
Upper tract infection
Lower tract infection
Complicated vs. Uncomplicated
causes and risk factors of UTI
Bacteria: E. Coli (70%-95% of cases that are uncomplicated), Staphylococcus, gram (+) bacteria
Indwelling Catheter- CAUTIs/HAI: gram (-) bacteria such as Klebsiella and Pseudomonas
Chronic antibiotic use
Diabetes
Sexual intercourse
Women/ Pregnancy
Compromised immune system
Aging
Immobility
BPH in men.
infection of urethra and cause
urethritis
sexual intercourse or viral infection
infection of bladder and cause
cystitis
causes puss and mucosa becomes hyperemic
Occurs in the renal parenchyma and collecting system (upper tract) caused by a bacterial infection usually beginning in the lower tract.
pyelonephritis
risk for chronic pyelonephritis
Reoccurring upper urinary tract infections
clinical manifestations of pyelonephritis
Lower UTI symptoms
Fever/chills
N/V
Malasie
Flank pain
CVA tenderness
risk factors for pyelonephritis
Failure to empty bladder
Obstruction
Immunosuppression
DM
Pregnancy
Neurologic disorders
Gout
AMS
clinical manifestations of upper and lower tract infections
Dysuria
Hesitancy
Intermittency
Post-void dribbling
Hematuria
Pyuria – puss
Incontinence
Nocturia
Urgency
Frequency
Upper and Lower Tract: Diagnostic Testing
Urinalysis
Clean Catch Urine or Straight Cath
+ nitrates, WBCs, leukocyte esterase, blood, cloudy urine
Pyelonephritis
Blood Studies
Elevated WBCs
Urine Cultures (antibiotic sensitivities)
Blood Cultures
Ultrasounds
CT scan
Kidney biopsy
Renal function panel
medical treatment for uncomplicated UTI 3 days
Fluoroquinolones (Levofloxacin, Cipro)
Nitrofurantoin (Macrodantin)
medical treatment complicated UTI
Ampicillin
Amoxicillin
Cephalosporins
medical treatment for fungus related to UTI
Fluconazole (Diflucan)
treatment of UTI symptoms
Urinary analgesic (phenazopyridine) - Relieve discomfort caused by dysuria.
medication education for management of UTIs
Medication compliance.
Side effects of antibiotics.
Clean perineal area.
Sexual health.
Void regularly
Fluid intake
Educate women.
Signs and symptoms of UTI/ infection.
Follow up care.
fluid management for UTIs
generous intake of fluid, 15ml per pound of body weight is minimumq
maintainence of acidic urine for UTIs
cranberry juice
vit C
bladder irritants to avoid with UTI
caffeine
alcohol
citrus juices
fever treatment for UTIs
NSAIDs and antipyretics
Care of a patient with Urinary Incontinence
Involuntary urinary leakage.
Bladder pressure is greater than urethral closure pressure.
OAB (overactive bladder)
causes of urinary incontinence
DIAPPERS stand for:
Delirium
Infection
Atrophic vaginitis
Psychological
Pharmacologic
Excess urine output
Restricted mobility
Stool impaction
risk factors for urinary incontinence
Neurogenic disorders
Spinal Cord dysfunction
Surgery
Medications
Stress
types of incontinence
functional
after trauma/surgery
overflow
reflex
stress
urge
iatrogenic
unable to get to bathroom in time
functional incontinence
PP, accidents, catheter, prostate, hysterectomy
incontinence after trauma or surgery
bladder doesn’t empty, pressure, obstruction, leakage
overflow incontinence
CNS – sphrincter relaxation
reflex incontinence
coughing, sneezing incontinence
stress incontinence
continuous need to pee
urge incontinence
medication side effects causes what incontinence
iatrogenic
inability to empty bladder
urinary retention
causes of urinary retention
Enlarged prostate
Tumor
Obstruction
Neurologic disorders
Diabetes
Medications
diagnostics of urinary retention
Bladder Log
Post Void residual – leftover urine after voiding
Urinalysis
treatment for urinary retention
Treat the cause
Kegel Exercises
Medication Therapy
Botox
Surgical Intervention/ Bladder sling
Schedule toileting
Double voiding
Straight Cath
uses for indwelling catheters
Urinary Retention
Inability to void
Obstruction
Bladder decompression
Accurate measurement of output
Prevent contamination
uses for straight cath
Relieve retention
Sterile sample
Measure postvoid residual
Neurogenic bladder
Bladder outlet obstruction in men
Every 3 to 5 hours
role of nurse in management of cathiterization
Peri care, infection prevention, monitor output, empty bag, placement
types of indwelling catherters
Ureteral Catheter
Suprapubic Catheter
Nephrostomy tubes