reinforcement - cc1 Flashcards

1
Q

Which kind of quality control involves the analyses of control samples together with patient’s specimens

A

Intralab/Internal quality control

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2
Q

Type of variation that present in all measurements due to chance and can be both positive or negative

A

Random

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3
Q

Systematic errors are due to

A

Improper calibration, expired reagents and test solutions

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4
Q

Delta check refers to

A

Comparison of patient’s previous result for discrepancy

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5
Q

Analytical testing performed outside the laboratory

A

Point of care or decentralized or bedside or alternate site testing

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6
Q

Types of discreet analyzers

A

Vitros, dimension

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7
Q

What analytes are increased in alcoholism

A

GGT, triglycerides, urates and others

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8
Q

Which anticoagulant has EDTA

A

Pink, tan, white

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9
Q

Insulin promotes

A

Lipogenesis, glycolysis, glycogenesis

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10
Q

Diabetes mellitus is diagnostic in

A

Random plasma glucose 250mg/dL and symptoms

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11
Q

Most common glycogen storage disease

A

Von gierke ; type 1a ; deficiency of glucose-6-phosphate

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12
Q

Type 1 hyperlipoproteinemia

A

Increased triglycerides and chylomicrons

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13
Q

B-Y bridging

A

Hepatic cirrhosis

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14
Q

Nephrotic syndrome

A

Decreased albumin, increased a2macroglobulin

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15
Q

Analyte tested for hepatic failure and Reye’s syndrome

A

Ammonia

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16
Q

What are the conditions associated in LD flipped pattern

A

Myocardial infarction, hemolytic anemia, renal infarction

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17
Q

First enzyme to increase in Myocardial infarction

A

CKMB

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18
Q

First cardiac marker to increase in Myocardial infarction

A

Myoglobin

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19
Q

Most specific marker for Myocardial infarction

A

Troponin I

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20
Q

Most specific substrate for Acid phosphatase ACP

A

Thymolpthalein monophosphate

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21
Q

Primary hypogonadism

A

Decreased testosterone, increased FSH and LH

22
Q

Secondary hypogonadism

A

Decreased testosterone, FSH, LH

23
Q

Primary hyperthyroidism

A

Decreased TSH, increased T3 and T4

24
Q

Thyrotoxicosis

A

Plummer’s disease

25
Q

Thyrotoxicosis

A

Decreased TSH, normal FT4, increased FT3 and T3

26
Q

Secondary hyperthyroidism

A

Increased TSH and FT4

27
Q

Primary hypothyroidism

A

Increased TSH, decreased T3 and T4

28
Q

Secondary hypothyroidism

A

Pituitary: Decreased TSH, T3, T4

29
Q

Tertiary hypothyroidism

A

Hypothalamus: Decreased TRH, TSH, T3, T4

30
Q

X-axis values are

A

Horizontal and independent

31
Q

Number of hours fasting is part of

A

Patient preparation

32
Q

Westgard rules: 1 2s is used for

A

Rejection and warning

33
Q

Visible light spectrum measures

A

400-700nm

34
Q

Major lipoproteins

A

Chylomicrons, VLDL, LDL, HDL

35
Q

Reference method for lipoprotein analysis

A

Ultracentrifugation, potassium bromide, 1.065spgr, Svedberg unit

36
Q

Electrophoretic pattern: a1 band

A

AAT, AAG TBG, HDL, Gc-globulin, AFP, A1-x

37
Q

Electrophoretic pattern: a2 band

A

a2macroglobulin, ceruloplasmin, haptoglobulin

38
Q

Electrophoretic pattern: B band

A

Hemopexin, LDL, complement, transferrin, B2microglobulin, fibrinogen

39
Q

Electrophoretic pattern: Y band

A

Immunoglobulin, CRP

40
Q

What is the CKMB pattern for myocardial infarction

A

Increased 4-8, peak 12-24, normal 48-72 hours

41
Q

What is the enzymatic nature of CK

A

Transferase

42
Q

Enzymes with enzymatic nature of Oxidoreductase

A

LDH, G6PD, MDH

43
Q

Enzymes with enzymatic nature of Hydrolase

A

ACP, ALP, LPS, Trypsin, Pepsin

44
Q

Enzymes with enzymatic nature of Lyase

A

Aldolase, Glutamate decarboxylase, Tryptophan decarboxylase

45
Q

Conversion factors: Uric acid

A

0.0595

46
Q

Conversion factors: Creatinine

A

88.4

47
Q

Conversion factors: Glucose

A

0.0555

48
Q

Conversion factors: IgM

A

10

49
Q

Trough is being measured by

A

Blood drawn immediately or 30 minutes before drug administration

50
Q

Newborn screening uses this specimen

A

Blood spot

51
Q

Classification of azotemia

A

Pre-renal, renal, post-renal

52
Q

What is the normal BUN:Crea ratio

A

10-20:1