Regulations Flashcards

1
Q

4 reasons animals are used in research

A

advance scientific understanding
models to study disease
develop and test therapies for disease
protect safety of people, animals, and environment

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2
Q

most animals used in research in Canada are used for this research type

A

fundamental research (57%)
others: development of products or services (17%), regulatory testing (4%), education and training (4%)

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3
Q

this is the national peer-review organization responsible for setting, maintaining, and overseeing the implementation of high standards of animal ethics and care in science in Canada:
guidelines and standards
institutional assessment and certification program
oversee animal care and use programs and provide accountability to the public
the guidelines have to be referenced when designing animal-based work to ensure compliance

A

CCAC Canadian Council on Animal Care

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4
Q

participating in ____ program and maintaining a ______ _________- is mandatory for all Canadian institutions who receive funding from CIHR, NSERC, SSHRC, most provincial funders and charitable organizations

A

CCAC; CCAC Certificate of Good Animal Practice

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5
Q

for CCAC, institutions are visited and inspected every ________ and assessed for their: compliance with CCAC guidelines, ethics review processes through ACCs, facility and animal care standards

A

3 years

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6
Q

what provincial legislation in Alberta makes direct reference to following CCAC guidelines

A

Animal Protection And and Regulation

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7
Q

federally, what protects animals from cruelty, abuse, and neglect in Canada

A

Criminal Code of Canada

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8
Q

federally, what protects animals and humans from animal-borne illness and disease, particularly livestock, in Canada

A

Health of Animals Act

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9
Q

federally, what requires that institutions maintain CCAc certification as a condition of funding research

A

Allocation of Tri-Council Funding

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10
Q

UofC policies exist to ensure that use of science adheres to _____ guidelines, policies, and standards; _______ professional codes and standards, and ______ standards of vet care

A

CCAC; ABVMA; CALAM

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11
Q

what association?
LAM vets are ____ members and follow practices outlined in this association’s Standard of Vet Care
it is a national association that provides training and educational resources to animal care workers in Canada
has lots go training and certification programs for people who work with animals in science

A

CALAM Cdn Assoc of LAM

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11
Q

what are the 3 Rs in humane animal use

A

replacement
refinement
reduction

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12
Q

what are some responsibilities of ACCs

A
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13
Q

these groups are responsible for ensuring that all use of animals in science aligns with the guidelines set forth by the CCAC, governmental legislation and regulations, as well as institutional policies, standards, and codes of ethical conduct

A

ACC animal care committees

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14
Q

these people are all members of

A

ACC animal care committees

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15
Q

what is this R

A

refinement

16
Q

what is this R

17
Q

what is this R

A

replacement

18
Q

what is the difference between absolute and relative replacement?

A

absolute refinement: no animals
relative refinement: use animals of lower sentience/considered incapable of experiencing suffering: Drosophila, nematodes, immature inverts
this category would include animals killed for food but you colelct some tissue samples that wouldn’t have been included otherwise

19
Q

what are animal use protocols, AUP

20
Q

what are these protocols called

21
Q

which category of invasiveness?
most inverts or live isolates

22
Q

which category of invasiveness?
little to no discomfort or stress, eg. performing a PE

23
Q

which category of invasiveness?
minor stress or pain of short duration. eg. blood draw

24
which category of invasiveness? moderate to severe stress or discomfort, eg. major surgery with analgesia given, induction of dz
D
25
which category of invasiveness? severe pain near, at or above pain tolerance threshold or unanesthetized conscious animals
E
26
difference between experimental/teaching endpoint and humane intervention point
27
what are 4 phases of AUP review process
ACC review of AUP ACC meeting application status modifications
28
protocol review: what main things to know
what is being proposed appropriateness of animals to accomplish this work track animal experience focus on welfare, 3Rs, improvements to animal experience, ensure practices meet standards
29
ACC reviews the _____ of the proposed animal work
ethics
30
funding agency or an independent review panel at institution evaluates the __________ of the proposed work, ie. the ______
importance and feasibility; merit
31
_______ is a responsibility shared by researchers, instructors, ACC, vets, and animal care staff; begins once AUP has been approved by ACC
post-approval assurance
32
what is this and who would perform
post-approval assurance by ACC
33
what are some activities that they can request