Introduction Flashcards
most LAM vets work in what sector
academia
which animal did Canadian educators work with the most in 2023
mice
This animal played an essential role in the development of chemotherapy treatments for leukemia, the most common cancer affecting children. Now, thanks to this and other advances, the survival rate for leukemia patients has skyrocketed from 30% to 80% today
lab mouse
- Small size
- Short reproductive cycle and lifespan
- Well characterized anatomy, genetics, biology and physiology
- Availability of genetically manipulated strains
- Stocks (outbred) and strains (inbred)
Nocturnal
Open rooted incisors, closed-rooted molars
Harderian glands
Two compartment stomach with simple intestines
High metabolism (no preanesthetic fasting)
Ability to concentrate urine; proteinuria
Thermoregulation *No sweat glands
*Large body surface area *Brown adipose tissue *Behavioural adaptations
What animal model does this describe?
mice
what are 4 common uses of mice in science
genetic diseases and conditions
infectious diseases
microbiome
immunology
What model species does this describe?
* Small size
* Short reproductive cycle and lifespan
* Docile and easy to train
* Known genetic background and microbial status
* Similarities to human disease conditions
* Nocturnal
* Open rooted incisors, closed- rooted molars
* Harderian glands
* Two compartment stomach with simple intestines
* No gallbladder
* Prone to phototoxic retinopathy
rat
what are common uses of rats in science
- Neuroscience (anxiety, depression, Parkinson’s, Alzheimer’s)
- Behavioural research (substance use disorders)
- Preclinical testing (pharmacology, toxicology
What is the animal?
Susceptibility to infectious diseases, carcinogens and tumours
* Cancer research (cheek pouch)
* Larger sized rodent
* Development of metabolic disorders and cardiomyopathy
* Behavioural research
* Open rooted incisors, closed-rooted molars
* Cheek pouches
* Flank glands
* Some strains hibernate
hamster
By studying this animal in the early 1900s, scientists discovered that vitamin C was essential to the human diet. To date, this animal’s contributions to research have led to over 23 Nobel Prizes in medicine.
what is it
guinea pig
what is this animal
* Docile, small size
* Auditory Research (large bullae)
* Reproductive Research (similar placenta and gestation
to humans)
* Respiratory Research (airways similar to humans and reactive to inhaled compounds)
* Dermatological Testing (hairless strain)
Open rooted incisors and molars
* Require vitamin C in their diet
* Absorb Ca in proportion to the amount in diet
* Fibrocartilaginous pubic symphysis
* Altricial newborn
* Heterophils
guinea pig
what is this animal
* Cardiovascular Research (diet-induced and genetic models of CV disease)
* Medical Device Testing (larger body size)
* Immunology & Antibody Production (large blood volume and easy access to vasculature)
* Ocular Research (large eye)
* Incisors and cheek teeth open rooted * Coprophagy
* Sensitive to hypercholesterolemia
* Heterophils
* Right AV valve is bicuspid
* Ca absorbed in proportion to amount in diet * Urine contains crystals
rabbit
true or false:
Zebrafish are one of the few fish that have been sent to space
true
true or false: * Zebrafish can repair their heart if the organ gets damaged
true
true or false: zebrafish can model human influenza virus to find treatments
true
true or false: Drunk zebrafish swim extra fast and get sober fish to follow them
true
what is this animal
Small size, ease of keeping large numbers
* Year-round spawning with large egg clutches * Translucent eggs with rapid development
* Fully sequenced genome
* Developmental Biology
* Tissue Regeneration
* Cancer Research
- Freshwater fish
- Adults are sexually dimorphic
- Embryos develop outside the mother and are optically transparent
- Sexually mature in 2-4 months
zebrafish
what is this animal
* Mucous and granular skin glands * Seat (drink) patches
* Have lungs
* Require vitamin A
* Wear gloves when handling! * Avoid phenolic disinfectants
African clawed frog
