Regulation of Water Balance Flashcards

1
Q

Which part of the body regulate water balance via the kidneys?

A

Hypothalamus

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2
Q

When the body experiences a fluid deficit or an increase in plasma osmolarity, what two things does the hypothalamus stimulate?

A

Thirst: Encouraging the individual to drink water.

Release of Antidiuretic Hormone (ADH): The posterior pituitary gland releases ADH under hypothalamic control.

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3
Q

How does ADH act on the kidneys?

A

Acts on the collecting ducts of the nephrons, promoting the reabsorption of water back into the bloodstream

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4
Q

What 2 hormones help regulate ECF volume?

A

ADH
Adrenal cortex hormones
cortisol & aldosterone

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5
Q

How does aldosterone help regulate ECF water balance?

A

Enhances sodium retention and potassium excretion

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6
Q

How does long-term steroid use lead to ECF volume excess?

A

Steroids can mimic the action of aldosterone, causing sodium retention

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7
Q

Primary organ for regulating fluid and electrolyte balance

A

Kidneys

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8
Q

Approximately, how much urine do the kidneys make per day

A

1.5 L

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9
Q

Daily water intake and output are between __ and __ mL

A

2000 and 3000 mL a day

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10
Q

What hormone in the cardiac system plays a role in fluid regulation?

A

Atrial natriuretic factor

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11
Q

What does atrial natriuretic factor to help regulate fluid balance?

A

It reduces sodium reabsorption in the kidneys, causing more sodium, and consequently water, to be lost in urine

By decreasing blood volume, ANF helps lower blood pressure

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12
Q

Which system accounts for most of the water intake?

A

GI

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13
Q

What does water intake include?

A

Fluids
Water from food metabolism
Water present in solid foods

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14
Q

Why do diarrhea and vomiting lead to significant fluid and electrolyte loss?

A

They expel lots of fluid and electrolytes

They prevent GI reabsorption of secreted fluids

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15
Q

What is insensible water loss?

A

Invisible vaporization from the lungs and skin that cannot be measured

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16
Q

Normal amount of insensible loss per day?

A

900 mL

17
Q

Insensible water loss should not be confused with?

A

Water excreted from sweat glands

18
Q

Four categories of causes of fluid imbalances?

A

ECF Volume Deficit
- increased loss
- decreased intake

ECF Volume Excess
- increased retention
- increated intake

19
Q

ECF Volume Deficit - Increased Loss

A

vomiting
diarrhea
fistula drainage
gi tract suction
third-spacing
overuse of diuretics
hemorrhage

20
Q

ECF Volume Deficit - Decreased Intake

A

nausea
anorexia
inability to drink
inability to obtain water

21
Q

ECF Volume Excess - Increased Retention

A

heart failure
cushing’s syndrome
liver disease
long-term use of corticosteroids
renal failure

22
Q

ECF Volume Excess - Increased Intake

A

rare when renal function is adequate
excessive IV administration of fluids