regulation of transcription and translation Flashcards

1
Q

what is a transcriptional factor

A

protiens wich move in from cytoplasm and bind to dna allowing transcription to occour

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2
Q

how is transcription regulated

A

via the binding of a transcrition factor

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3
Q

describe and explain the role of a transcrition factor

A
  • transcription factor in cell diffuses into the nucleas
  • transcriptional factor binds to DNA
  • binding of transcriptional factor to DNA enables RNA polymerase to bind to dna
  • binding of RNA polymerase enables transcription
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4
Q

describe the role of eostrogen in regulation of transcription and translation

A
  • eostrogen lipid soluable so can easily diffuse through cell surface membrane
  • eostrgen complementry tertiary structure to receptor on transcriptional factor
  • eostrogen binds to receptor on transcriptional factor forming oestrogen-oestrogen recptor complex
  • diffuses through to nucleus and binds with specific dna sites at the start of target gene
  • enables RNA polymerase to bind to dna
  • transcription can occour
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5
Q

where does transcriptional factor bind ond dna

A

specific DNA sites at the start of the target gene

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6
Q

what is oestrogen that makes it lipid soliuable

A

its a steroide hoemone

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7
Q

what is siRNA

A
  • siRNA double trand that untwists and binds to mrna
  • binds to mrna via complementry base pairing
  • cuts up mRNA preventing translation
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8
Q

what is miRNA

A

-similar to siRNA binds to mRNA
- binds to mRNA and uses protien to block tRNA from binding to mrna
- preventing translation

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