regulation of transcription and translation Flashcards
1
Q
what is a transcriptional factor
A
protiens wich move in from cytoplasm and bind to dna allowing transcription to occour
2
Q
how is transcription regulated
A
via the binding of a transcrition factor
3
Q
describe and explain the role of a transcrition factor
A
- transcription factor in cell diffuses into the nucleas
- transcriptional factor binds to DNA
- binding of transcriptional factor to DNA enables RNA polymerase to bind to dna
- binding of RNA polymerase enables transcription
4
Q
describe the role of eostrogen in regulation of transcription and translation
A
- eostrogen lipid soluable so can easily diffuse through cell surface membrane
- eostrgen complementry tertiary structure to receptor on transcriptional factor
- eostrogen binds to receptor on transcriptional factor forming oestrogen-oestrogen recptor complex
- diffuses through to nucleus and binds with specific dna sites at the start of target gene
- enables RNA polymerase to bind to dna
- transcription can occour
5
Q
where does transcriptional factor bind ond dna
A
specific DNA sites at the start of the target gene
6
Q
what is oestrogen that makes it lipid soliuable
A
its a steroide hoemone
7
Q
what is siRNA
A
- siRNA double trand that untwists and binds to mrna
- binds to mrna via complementry base pairing
- cuts up mRNA preventing translation
8
Q
what is miRNA
A
-similar to siRNA binds to mRNA
- binds to mRNA and uses protien to block tRNA from binding to mrna
- preventing translation