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ANSC 3122 > Regulation Of Reproduction > Flashcards

Regulation Of Reproduction Flashcards

0
Q

Leydig cells

A

Testosterone production

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1
Q

Seminiferous tubules

A

Spermatogenesis

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2
Q

Sertoli cells

A

Produce AMH in response to TDF

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3
Q

Releasing hormones

A

Production and release from hypothalamus, hypothalamo-hypophyseal portal blood system brigs them to anterior pituitary causing the synthesis and release of hormones from the anterior pituitary gland

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4
Q

Hypothalamic GnRH

A

Stimulates anterior pituitary to produce and release LH and FSH

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5
Q

Hypothalamic GHRH

A

Stimulates anterior pituitary to produce and release growth hormone

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6
Q

CRH

A

Stimulates anterior pituitary ACTH

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7
Q

TRH

A

Stimulates anterior pituitary TSH

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8
Q

Oxytocin and antidiuretic hormone

A

Small hormones produced by specific nerves within the hypothalamus, travel along nerve axons which terminate in the posterior pituitary gland, stored until appropriate stimulus

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9
Q

Hormonal classification

A

Source, mode of action, biochemical classification

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10
Q

Sources of reproductive hormones

A

Hypothalamus, pituitary gland, gonads, uterus and placenta

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11
Q

Mode of action for reproductive hormones

A 
Release of other hormones (RH)
Stimulation of gonads (gonadotropins)
Sexual promotion (steroids)
Pregnancy maintenance 
Luteolysis
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12
Q

Biochemical classification

A

Peptides/proteins/glycoproteins
Steroids
Prostaglandins

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13
Q

Peptide hormones

A

Simple amino acids; oxytocin and GnRH

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14
Q

Glycoproteins hormones

A

Contain carbohydrate moieties; FSH, LH, TSH
Alpha and beta subunit with CHO attached to each
Beta chain varies

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15
Q

Protein hormone characteristics

A

Long chains of AAs
Water soluble
Heat labile

16
Q

Pituitary gonadotropins

A

LH and FSH

17
Q

Prolactin

A

Protein

18
Q

hCG

A

Glycoprotein

19
Q

PMSG

A

Glycoprotein

20
Q

Relaxin

A

Protein

21
Q

Steroid hormones

A

Produced by the testis, ovaries, placenta and adrenal glands

All derived from cholesterol

22
Q

Steroid characteristics

A

Lipid soluble
Heat stable
Small molecule

23
Q

Progestins (progesterone)

A

21 carbons

24
Q

Androgens

A

19 carbons

25
Q

Estrogens

A

18 carbons

26
Q

Cholesterol

A

27 carbons; majority in cell membranes

27
Q

Side chain cleavage enzyme

A

Removes side chain from carbon to result in 21 carbon molecule pregnenolone

28
Q

3-beta-HSD

A

Pregnenolone OH group changed to doubled bonded O, results in progesterone, another 21 carbon molecule

29
Q

Progesterone metabolism

A

2 carbons cleaved resulting in testosterone a 19 carbon molecule

30
Q

Aromatase

A

Testosterone loses methyl group, O becomes OH, two double bonds gained resulting in estradiol, a 18 carbon molecule

ANSC 3122 (4 decks)

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