regulation of hormone secretion into blood Flashcards
humoral stimulus
stimulus is released in response to changes in ion con. or nutrient level in blood
humoral stimulus e.g 1
INCREASE BLOOD GLUCOSE ( AFTER EATING CARBS )
pancreatic B-cells ( of islets of langerhans ) detect glucose and release insulin - > decreases blood glucose
humoral stimulus e.g 2
DECREASE BLOOD Ca+
parathyroid gland detects decrease in Ca+ and releases parathyroid hormone => increase bone resorption (breakdown) by - decrease osteoblast activity and increase in osteoclast activity => increases blood Ca+
neural stimulus
e.g. 1 Heart Rate (HR)
- at rest - heart is stable
- then it experiences a stimulus activating SNS
3.SNS sends signals by preganglionic neurons using nt = acetylcholine (ach) directly to adrenal medulla
4.adrenal medulla releases epinephrine + norepinephrine (NE)
- causing INCREASE HR + FORCE OF CONTRACTION
neural stimulus
e.g. 2 uterine contractions
- uterine contractions stimulate -> hypothalamus which signals the post. pituitary
- post. pituitary releases oxytocin
- release of oxytocin further stimulate uterine contraction = +ive fb, where contractions intensify until childbirth
hormonal stimulus
e.g metabolism
low metabolism
1.hypothalamus releases thyrotropin releasing hormone (TRH)
- TRH stimulates ant. pituitary to release thyroid stimulating hormone (TSH)
- TSH acts on thyroid gland
4.thyroid gland secretes thyroxin (T4)
5.T4 converted to T3 (in target tissue/liver)
= increase in metabolism
=-ive fb