Regulation Of Feeding 12

Question 1

What is satiety?

Answer 1

The feeling of fullness from hormones

Question 2

What is the central melanocortin system?

Answer 2

The combination of AGRP and alpha-MSH acting on the melanocortin-4 receptor

Question 3

What happened in the conditioned study on mice looking at food preference?

Answer 3

Used mice that did not change NPY/AGRP neural activity

Conditioned to a food source- given pulses to make them feel hungry even when feeding

When given a choice the mouse didn’t choose the food conditioned to- suggests hunger is uncomfortable

Question 4

What is the appetitive behaviour seen in hamsters?

Answer 4

Food hoarding

Question 5

What are the differences in the behavioural effects of NPY and AGRP?

Answer 5

AGRP primarily regulates the long term appetitive behaviour of hoarding, whereas NPY only increases foraging and food intake over a shorter period

Question 6

What is different about birds and Leptin?

Answer 6

Leptin is less likely to be a key nutritional signal in birds and probably acts locally in tissues rather than circulating in the blood