Regulation of ATP production Flashcards
factors to consider in atp production
ration of atp: app
ration of NAD:NADH2
amount of oxygen available to the cell
rate of limiting enzymes
short version of cellular respiration
C6H12O6+ 6O2==6CO2+ 6CO2+ 36 ATP
what is the rate limiting enzyme of glycolysis
PKF
positive modulated of glycolysis
ADP
negative modulator of Gylcolysis
ATP
what is the rate limiting enzyme of the prep step
PDC
positive modular of prep step
NAD
negative modular of prep step
NADH2
what happens if lots of oxygen is available
lots of atp is produced
atp is a negative modulator and blocks PFK
cellular NAD increases and enhances PDC causing lots of pyruvate to be oxidized
What happens if little or no oxygen is available
little to no ATP produced through oxidative phosphorylation ADP enhances PFK
NADH2 increases and inhibits PDC
glycolysis must convert pyruvate to lactic acid