Red Blood Cell and Platelet Preservation

Question 1

What is the maximum amount of blood that can be collected from a 110-LB donor, including samples for processing?

Answer 1

525 ML

Question 2

How often can a blood donor donate blood?

Answer 2

EVERY 8 WEEKS

Question 3

When RBCs are stored, there is a “shift to the left” this means?

Answer 3

Hemoglobin-Oxygen affinity increases owing to decrease in 2,3 DPG

Question 4

Anticoagulant preservatives that provides a storage time of 35 days at 1 C 6 C for units of whole blood and prepared RBCs if an additive solution is not added?

Answer 4

CPDA-1

Question 5

Current storage time and storage temperature for platelet concentrates and apheresis platelet components?

Answer 5

5 days at 20 C to 24 C

Question 6

RBCs can be frozen for?

Answer 6

10 YEARS

Question 7

Whole blood and rbc units are stored at what temperature?

Answer 7

1 C to 6 C

Question 8

one criterion used by the FDA for approval of new preservation solutions and solution and storage containers in an average 24- hour post transfusion rbc survival of more than?

Answer 8

75%

Question 9

What is the lowest allowable pH for a platelet component at outdate?

Answer 9

6.2

Question 10

What occurs during the storage of red blood cells?

Answer 10

pH decreases

Question 11

Approved for bacterial detection specific to extending the expiration of apheresed platelets to 7 days?

Answer 11

PAN GENERA DETECTION TEST (PGD)

Question 12

Most common cause of bacterial contamination of platelet products?

Answer 12

Entry of skin plugs in the collection bag

Question 13

The INTERCEPT pathogen reduction system uses method?

Answer 13

Amotosalen and UV Light

Question 14

approved preservative solutions for storage of RBCs ar 1 C to 6 C for 21 Days?

Answer 14

ACD, CPD, CP2D

Question 15

Additive solutions that are approved in the US for RBC storage for 42 days?

Answer 15

ADSOL, NUTRISOL, OPTISOL, SOLX

Question 16

Only FDA approved rejuvenation solution used in some blood centers

Answer 16

REJUVESOL

Question 17

CHELATES CALCIUM, PREVENTS CLOTTING

Answer 17

Citrate

Question 18

Maintains pH during storage; necessary for maintenance of adequate levels of 3,3- DPG

Answer 18

Monobasic Sodium Phosphate

Question 19

Substrate for ATP production (cellular energy)

Answer 19

DEXTROSE

Question 20

Production of ATP (extends shelf life from 21-35 days)

Answer 20

ADENINE

Question 21

Ratio of SODIUM (NA)

Answer 21

1:12

Question 22

Ratio of Potassium K

Answer 22

25:1

Question 23

Primary function is gas transport?

Answer 23

Hemoglobin

Question 24

Minimum number of platelets required in a platelet concentrate prepared from whole blood by centrifugation (90% of sampled units) ?

Answer 24

5’5 - 10’10

Question 25

Minimum number of platelets required in an apheresis component?

Answer 25

3_10'11

Question 26

Frozen and Thawed RBCs processed in an open system can be stored for how many days/hours?

Answer 26

24 hours

Question 27

Discovered the ABO Blood groups

Answer 27

Karl Landsteiner

Question 28

In what year blood was taken from 3 young men and given to the stricken pope innnocent VII?

Answer 28

1492

Question 29

First to suceeded vein to vein transfusion

Answer 29

Edward E. Lindemann

Question 30

3 units of whole blood

Answer 30

Packed RBC, Plasma, Platelet

Question 31

What is the hemoglobin source for hemoglobin based- oxygen carriers in clinical testing?

Answer 31

Both Bovine and human hemoglobins

Question 32

Nucleic Acid Amplification Testing is used to test donor blood for?

Answer 32

HEPATITIS C, HIV, West Nile virus