Rectal Bleeding Flashcards

1
Q

What is the first priority when assessing patients with rectal bleeding

A

ABCDE
Specifically C
hypotension, tachycardia, cool peripheries, tachypnoea, decreased consciousness - must resuscitate

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2
Q

What are the anorectal differentials for Rectal bleeding

A
Haemorrhoids
Rectal/anal tumour 
Anal fissure
Anal fistula 
Solitary rectal ulcer 
Radiation proctitis 
Rectal varices
Trauma
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3
Q

What are the colonic differentials for rectal bleeding

A
Diverticular disease
Angiodysplasia
Inflammatory/ischaemic/infective colitis 
Colonic tumour 
Iatrogenic 
Vasculitis
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4
Q

What are the ileo-jejunal differentials for rectal bleeding

A
Coeliac
Aorto-enteric 
Small-bowel tumours
Crohn's
AV malformation
Angiodysplasia 
Peptic ulcers
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5
Q

What are the upper-GI differentials for rectal bleeding

A
Mallory-Weiss tear
Peptic ulcers
Aorto-enteric fistula 
Dieulafoy lesions
Osler-Weber-Rendu sundrome
Gastritis/duodenitis
Tumour 
Varices
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6
Q

What questions should be asked about rectal bleeding itself

A

How much blood has been passed + hypovolaemia symptoms

What is the duration and frequency of symptoms

What does the blood look like

What is the relationship of blood with stool

Is there any pain or prolapse

Is there any tenesmus

Has there been a change in bowel habit

Any weight loss

Any anaemia symptoms?

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7
Q

What does the relationship of blood with stool suggest

A

Blood mixed with stool: lesion proximal to the sigmoid

Blood streaked on stool: sigmoid or anorectal source

Blood separate from stool immediately after: haemorrhoids

Blood separate from stool completely: diverticular disease, angiodysplasia, IBD, rapidly bleeding cancer

Blood only seen on toilet paper: haemorrhoids, fissure

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8
Q

What does pain/no pain or prolapse suggest with rectal bleeding

A

Pain - excruciating pain: anal fissure/anal herpes

Abdominal cramping: colitis

Most conditions causing bleeding are painless e.g. haemorrhoids

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9
Q

What is mucous passage associated with (with rectal bleeding)

A

Colitis
Proctitis
Rectal cancer
Villous adenomas of the rectum

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10
Q

What are the most common causes of rectal bleeding

A
Diverticular disease
Angiodysplasia 
Haemorrhoids 
Colitis 
Anal fissures 
Lower GI tumours
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11
Q

What should be asked about past medical history for rectal bleeding

A
Previous rectal bleeding
Ulcerative colitis 
Recent bowel trauma 
Aortic surgery 
Radiotherapy to the rectum 
Bleeding tendency (warfarin, blood thinners, haemophilia, platelet disorders etc.)
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12
Q

What drugs should be asked about for rectal bleeding

A

Anticoagulants or antiplatelets
NSAIDs (peptic ulcer or diverticular disease)
Bisphosphonates, aspirin, steroids (peptic ulcers)
Antibiotic or PPI use (C. diff -> infectious colitis)
Beta blockers (attenuate cardia response to hypovolaemia)

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13
Q

What should be looked for on exam for rectal bleeding

A

Is the patient haemodynamically stable?
Chronic blood loss signs - koilonychia (IDA), pallor
Malignancy signs - lymphadenopathy, cachexia
Focal tenderness or masses - check for malignancy

DRE - fissures, skin tags, sentinel pile haemorrhoids, fistula
Feel for palpable mass, observe for blood on gloved finger

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14
Q

Investigations for rectal bleeding?

A

FBC - ?anaemia ?platelets
Clotting - ?bleeding tendency
Group + save - if haemodynamically unstable
Urea - Raised - recent upper GI bleed (from breakdown of RBCs)

Endoscopy ± rigid sigmoidoscopy
Pathway of imaging: colonoscopy -> mesenteric or CT angiography -> radionuclide imaging

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15
Q

What is angiodysplasia

A

Submucosal arteriovenous malformation (acquired)
Predominance in the right colon
Lesions typically <1cm , but may bleed out of proportion to size
Results in venous blood loss
Produces a characteristic “cherry red spot” appearance on endoscopy (but blood will frequently obscure the field of view in acute haem)

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16
Q

What is the management for haemorrhoids

A

Lifestyle modification: increase fibre, minimise straining, keep hydrated

Medical: local anaesthetic, steroidal creams, laxative therapy for constipation

Surgical: Rubber band ligation, injection sclerotherapy, infrared coagulation/photocoagulation
Haemorrhoidectomy

17
Q

What is the typical presentation for diverticular disease and angiodysplasia

A

Large, non-painful, bright red rectal bleed with no associated symptoms

18
Q

What are the surgical options for diverticular disease

A

Hartmann’s (end colostomy) + rectal stump

Hartmann’s (end colostomy) + mucous fistula

Primary anastamosis

19
Q

What is the medical management for anal fissures

A
High fibre diet + laxatives/non-constipating analgesics
topical anaesthetics e.g. lidocaine gel
Topical GTN (increased local blood flow and relax the internal anal sphincter) 
Topical diltiazem (CCB) if GTN intolerable due to headache 
Botox injection to the anal sphincter to relieve spasm
20
Q

What is the surgical management for persistent deep anal fissures

A

Lateral internal sphincterotomy

Anal advancement flap

21
Q

What is the anatomical definition of lower GI haemorrhage

A

Bleeding that arises distal to the ligament of Treitz at the duodenojejunal junction

22
Q

How are internal haemorrhoids classified

A

Grade I: no prolapse
Grade II: prolapses on straining and reduces spontaneously on cessation
Grade III: prolapses and requires manual reduction
Grade IV: permanent prolapse, irreducible

23
Q

What are the differentials for a patient with known haemorrhoids who has acute anal pain

A
Thrombosed external haemorrhoid
Anal fissure 
Proctalgia fugax 
Anal abscess
Lower anal cancer
24
Q

What are the risk factors for colorectal carcinoma

A

Age
Males (Rectal only)
Central obesity
Colorectal disease: IBD, previous history, polyps, irradiation
Familial: FAP, HNPCC, Peutz-Jeghers, juvenile polyposis, Cowden’s, MYH-related polyposis
Sedentary lifestyle

25
Q

What is the significance of ordering CRP with iron studies in anaemia investigations

A

Ferritin is an acute phase reactant, which may be elevated by infection, inflammation or malignancy + increased alcohol consumption
Assessing CRP allows you to identify whether ferritin is raised due to IDA or another process