Flank Pain Flashcards

1
Q

Differentials for flank pain

A
Muscular sprain
Nephrolithiasis/ureteric colic 
Spinal pathology (fractures, metastases, disc prolapse)
Leaking/ruptured AAA
Testicular torsion 
Pyelonephritis 
Perforated peptic ulcer 
Renal ulcer 
Abscess
Basal pneumonia
Ectopic pregnancy
Ovarian torsion
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2
Q

What is the site of kidney stone pain

A

Almost always unilateral, but location may radiate from loin to groin

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3
Q

What can the character of flank pain suggest

A

Colicky pain - ureteric stone
Constant - stone lodged in the kidney or inflammatory cause
Ache - musculoskeletal
Shooting pain - nerve impingement

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4
Q

What does pain that radiates down the leg suggest

A

Lumbar nerve root pain

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5
Q

What associated symptoms should be asked for with flank pain

A
Fevers, rigors, night sweats 
Dehydration
N+V
Haematuria 
LRTI symptoms
Cloudy or offensive smelling urine
Leg weakness
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6
Q
What do the following symptoms (with flank pain) suggest: 
Fevers, rigors and night sweats
Dehydration
N+V 
Haematuria
LRTI symptoms
Cloudy or offensive smelling urine
Leg weakness
A

Fevers, rigors and night sweats: pyelonephritis or malignancy e.g. Renal CC
Dehydration: predisposes kidney stones
N+V : ureteric stones, biliary colic, may be due to musc pain
Haematuria: microscopic - ureteric stones
LRTI symptoms: UTI or obstruction
Cloudy or offensive smelling urine: Infection
Leg weakness: Spinal pathology

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7
Q

What should be asked about in the past medical history for flank pain

A
Previous kidney stones (recurrence)
Recurrent cystitis (struvite stones)
Atherosclerotic disease (AAA)
Long-standing back pain (musc, ligament, bone)
Kidney disease (PKD -> pyelonephritis)
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8
Q

What drugs should be asked about specifically in a history for flank pain

A

Aciclovir and idinavir - may crystallise in the urine

Acetazolamide causes diuresis and potentially dehydration, predisposing to stone formation

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9
Q

What is being looked for on exam of a patient with flank pain

A

Position - colic (writhing in pain) or peritonitis (still)
Tendereness - flank/loin tenderness may be renal or ureteric stones
Masses - Look for expansale pulse - AAA
Spine and range of movement
Lowe limbs - spinal pathology or vascular pathology
Temperature - indicates whether it is inflammatory e.g. pyelonephritis is ongoing

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10
Q

What investigations should be done for suspected ureteric colic

A

Urinalysis and MC+S IF abnormal

FBC
CRP
U+Es - assess renal function
Calcium, phosphate and urate - aetiology of kidney stones

USS (Assess for AAA)
Non-contrast KUB - stones in the kidney or ureter or any obstructions or AAA

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11
Q

What imaging is used for stones in pregnant women

A

Magnetic resonance urogram (MRU)

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12
Q

What does pH of the urine suggest

A

Acidic - urate stone

Alkali - Urease-producing bacteria e.g. proteus, pseudomonas, klebsiella that predispose to stone formation

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13
Q

What indicates admission for a patient with a kidney stone

A

Evidence of URTI (cloudy urine, white cell clasts, high WCC, fever, high CRP)

Evidence of renal impairment/failure (Cr, Ur)

Refractory pain despite analgesia

Bilateral obstructing stones

Patient is elderly, a child, or otherwise unwell (unable to tolerate oral fluids)

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14
Q

What is the management for kidney stones

A

Regular multimodal analgesia e.g. paracetamol + NSAIDs

Encourage fluid intake

Tamsulosin (alpha-B) or nifedipine (CCB) to relax the ureter smooth muscle and increase chance of spontaneous passage, more useful in distal stones

Active stone removal if >5mm, if not ask to strain and follow up in 2-3 weeks + assessment if it shows up on radiograph

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15
Q

What is the determinant for active stone removal and how is it done

A

Stones >5mm

Lithotripsy (extracorpeal shock wave lithotripsy/ESWL) - renal <2, ureteric <1

Ureterorenoscopic removal with dormia basket, holmium laser, mechanical lithotripsy etc.

Percutaneous nephrolithotomy (rare as invasive)

Stenting (using JJ stent) to prevent hydronephrosis

Antibiotic cover for invasive procedures

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16
Q

What are the indications for further investigations of ureteric colic

A

Strong family history
Multiple stones at first diagnosis
Recurrent stone formation/passage

17
Q

Patient with dull ache in the right flank with urinary frequency, dysuria and fever + vomiting
Urine dip shows haematuria, pyuria and nitrites

A

Acute pyelonephritis (often E.coli)

18
Q

What should be looked out for in monitoring for an intrarenal or perinephric abscess

A
Persistently high fever
Bacteraemia
Very high initial WCC
Severe tenderness on examination
Failure to improve after the appropriate therapy
19
Q

50M with high BMI who has right flank pain. Present for a week without specific trigger. Ache, worse in the morning or after a long day’s drive. Ibuprofen helps a bit, but only temporary fix. No associated symptoms. What is the diagnosis and how should it be managed

A

Musculoskeletal back pain (affects 80% of the population at some point)

Maintain activity and exercise
Regular multimodal analgesia
Build up core muscles
Weight loss
General back care
Avoid surgery
20
Q

What are the different types of kidney stones

A

Calcium (75-85%)
Struvite (10-20%)
Urate (5-10%)
Cystine (1%)

21
Q

How are calcium stones treated

A

Hypercalciuria - investigate for hyperPTH, thiazides, low calcium diet

Hyperuricosuria - allopurinol

Hypocitraturia - potassium citrate

22
Q

What medical conditions predispose to stone formation

A

Metabolic (hypercalciuria, uricosuria, citraturia, oxaluria, gout, cystinuria)
Primary hyperparathryoidism
Crohn’s (oxalate stones)
Chronic UTI due to urease-producing bacteria (struvite)
Medullary sponge or polycystic kidneys
Renal tubular acidosis
Sarcoidosis

23
Q

What radiographic findings would be looked for in a patient with stones

A

The stone themselves
Hydronephrosis and/or hydroureter (dilated ureter) due to obstruction
Perinephric fluid
“soft-tissue rim sign” - stones surrounded by rim of soft tissue, differentiating ureter stones from a calcific pelvic vein (phlebolith)

“tail sign” - soft tissue opacity extends away from the stone like a tail, consistent with pelvic phlebolith - NOT a stone

24
Q

What are the complications of kidney stones?

A
Ureteric stricture
Acute or chronic pyelonephritis 
Renal failure 
Intrarenal or perinephric abscess
Xanthogranulomatous pyelonephritis
Urine extravasation
25
Q

Contraindications to NSAIDs

A
Asthma
History of anaphylaxis
Previous or active peptic ulcers
Severe heart failure
COX-2 selective inhibitors cannot be used in IHD, cerebrovascular disease or peripheral arterial disease
26
Q

Cautions to NSAID use

A

Coagulation defects
Renal, cardiac or hepatic impairment
Pregnancy and breast-feeding
Elderly patients

27
Q

Where are stones most likely to cause obstruction in the urinary tract

A

Pelvo-uteric junction (PUJ)
Pelvic brim
Vesico-uteric junction (VUJ)

28
Q

What are the indications for surgery on an AAA

A

diameter >5.5cm
Growing >1cm per year
Symptomatic

29
Q

What are the red flags for back pain that require immediate referral for further investigation

A

Sphincter problems

Unable to self-care or walk

30
Q

What are the red flags for back pain that require referral within a week for further investigation

A
Weight loss
Fever
Back tenderness on palpation
Thoracic spinal pain
Violent trauma
31
Q

What are the red flags for back pain that require referral ASAP for further investigation

A

Age <20 or >50
Severe morning stiffness
Structural deformity e.g. scoliosis
Nerve root pain not resolving >6 week