Recreational drugs Flashcards
what is synaptic transmission?
- messengers are passed from one neuron to another
- information is passed down the axon of the neuron as an electrical impulse - action potential
how does action potential work?
- information is passed down the axon of the neuron as an electrical impulse - action potential
- the action potential reaches the end of the axon it needs to be transferred to another neuron
how do neurotransmitters and dopamine relate?
- Dopamine is an excitory neurotransmitters
- released from your reward pathway in your brain
- become addicted to the feeling dopamine gives you
what is agonist?
Mimics the effect of neutransmitters, they bind to the receptors to excite the neuron so it seems more or the natural neutransmitter released, increasing action potential
what is antagonist?
Reduces the effect or stops the effect of NT, binds to the receptors to block them to stop messages from being passed on or to slow it down
what is a reuptake inhibitor?
Blocks the reuptake of the NT, do more NT stays in the synpase increasing its action
what is the drug heroin made from?
morphine
what was the drug heroin originally used for?
To treat pain, sleeplesssness
How does heroin impact neurotransmission?
- binds to the presynpatic neurons that use dopamine as a NT
- Heroin changes the action of dopamine in the reward pathway, releasing more dopamine than usual
- morphine binds to the receptors, inhibitory effect of GABA on dopamine neuron
- dopamine activity increases release of dopamine into the synpatic cleft
- floods the endorphin receptors and stimulates
How does heroin change its behaviour short term?
- produces feelings of well being
- reduction of pain
- pleasure of feelings
what are the long term effects of the heroin on neurotransmission?
- extreme weight loss
- heart and kidney problems
- mood swings
How does the drug apthetamine impact neurotransmission?
- noradrenaline, dopamine and serotonin are quickly released in the brain, feeling of reward, improved mood, sudden rush of adrenaline
- temporarily prevents neurotransmitters from being cycled.
- increases concentration of dopamine in the synaptic gap
- enters the terminal button
- excites dopamine neurons via the glutamate neurons
may reduce the inhibitory effect of glutamate - makes neurons more readibly excitable
how does apthetamine affect the behaviour short term?
- Increased heart rate
- increased blood pressure
- decreased appetite
- dilated pupils
- feeling happiness
what are the long term effects of apthetamines on neurotransmissions?
- causes someone to abused this drug to avoid feelings
- receptors become damage
- will lead to addiction
what is the reward pathway?
- involved in the mesolimbic pathway
when dopamine is released, encourages your body to do it again
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