Recreational Drugs Flashcards

3.1.2 The effect of recreational drugs on the transmission process in the central nervous system.

1
Q

Identify 2 drugs that can affect the transmission process.

A

Cocaine and Heroin

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2
Q

Describe the effects cocaine has on the body.

A

Stimulant effect: feelings of euphoria and pleasure.

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3
Q

How does cocaine affect neurotransmitters and synaptic transmission?

A

It alters synaptic transmission by blocking the reuptake of dopamine. The synapse is then flooded with dopamine.

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4
Q

What are the long-term effects of cocaine?

A

Dopamine receptors will become downregulated, meaning fewer receptors are active and the quantity of dopamine declines (explaining withdrawal).

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5
Q

Describe the effects of heroin on the body.

A

Depressant effects on the CNS, slowing down its activity (including pain).

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6
Q

How does heroin affect neurotransmitters and synaptic transmission?

A

Once heroin reaches the brain it becomes morphine which binds with the natural opioid system to enhance the natural response.

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7
Q

Define agonist.

A

A drug that mimics the action of another natural biochemical.

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8
Q

Define antagonist.

A

An antagonist drug binds to receptors in the brain and prevents an agonist from having a reaction.

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9
Q

What are the long-term effects of heroin?

A

Regular use of heroin over time means opioid receptors on post-synaptic neurons are desensitised, creating tolerance.

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10
Q

What is the supporting evidence of the effect of recreational drugs?

A

Olds + Milner
Mice endured pain in order to receive stimulation in the reward pathway. This demonstrates the idea of a reward pathway in the brain that overrides the effect of pain for pleasure.

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11
Q

What is the different theory of the effect of recreational drugs?

A

Jones and Stones
Gave regular cannabis users marijuana or a placebo and found there was no difference in effect.
= Not only biological factor that affects neurotransmission.

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12
Q

What is the opposing evidence of the effect of recreational drugs?

A

Studies that support the effect of recreational drugs are mainly animal studies, which lack generalizability as their brains are qualitatively different to ours.

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