Recombinant cytokines and their uses Flashcards

1
Q

Aldesleukin (IL-2)

A

RCC, metastatic melanoma

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2
Q

Epoetin alfa (erythropoietin)

A

Anemias (especially in renal failure)

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3
Q

Filgrastim (G-CSF)

A

Recovery of bone marrow

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4
Q

Sargramostim (GM-CSF)

A

Recovery of bone marrow

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5
Q

IFN-alpha

A

Chronic HBV, HCV, (think IFN a-B-C) Kaposi sarcoma, malignant melanoma

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6
Q

IFN-beta

A

MS

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7
Q

IFN-gamma

A

CGD (stimulates/ initiates Mphages- since neutrophils are not working properly)

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8
Q

For thrombocytopenia

A

Use thrombopoietin receptor agonists or IL-11

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