Recombinant cytokines and their uses Flashcards
1
Q
Aldesleukin (IL-2)
A
RCC, metastatic melanoma
2
Q
Epoetin alfa (erythropoietin)
A
Anemias (especially in renal failure)
3
Q
Filgrastim (G-CSF)
A
Recovery of bone marrow
4
Q
Sargramostim (GM-CSF)
A
Recovery of bone marrow
5
Q
IFN-alpha
A
Chronic HBV, HCV, (think IFN a-B-C) Kaposi sarcoma, malignant melanoma
6
Q
IFN-beta
A
MS
7
Q
IFN-gamma
A
CGD (stimulates/ initiates Mphages- since neutrophils are not working properly)
8
Q
For thrombocytopenia
A
Use thrombopoietin receptor agonists or IL-11