Recombinant Antibodies Flashcards
1
Q
Alemtuzumab target
A
CD52
2
Q
Alemtuzumab use (2)
A
CLL, MS
3
Q
Bevacizumab target
A
VEGF
4
Q
Bevacizumab use (3)
A
Colorectal cancer, renal cell carcinoma, Neovascular age-related macular degeneration
5
Q
Cetuximab target
A
EGFR
6
Q
Cetuximab use (2)
A
Stage IV colorectal cancer, head and neck cancer
7
Q
Rituximab target
A
CD20
8
Q
Rituximab use (4)
A
B-cell non-Hodgkin lymphoma, CLL, rheumatoid arthritis, ITP
9
Q
What drugs increases risk of progressive multifocal leukoencephalopathy.
A
Rituximab and Natalizumab
10
Q
Trastuzumab target
A
HER2/neu
11
Q
Trastuzumab use
A
Breast cancer
12
Q
Adalimumab, certolizumab, infliximab target
A
Soluble TNF-α
13
Q
What drug is a decoy TNF-α receptor and not a monoclonal antibody
A
Etanercept
14
Q
Eculizumab target
A
Complement protein C5
15
Q
Eculizumab use
A
Paroxysmal nocturnal hemoglobinuria
