HLA Subtypes Flashcards

1
Q

HLA A3

A

Hemochromatosis

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2
Q

HLA B8 (2)

A

Addison disease, myasthenia gravis.

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3
Q

HLA B27 (4)

A

PAIR, Seronegative Arthropathies

Psoriatic arthritis, Ankylosing spondylitis, IBD-associated arthritis, Reactive arthritis

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4
Q

HLA DQ2/DQ8

A

Celiac Disease

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5
Q

HLA DR2 (4)

A

Multiple sclerosis, hay fever, SLE, Goodpasture syndrome.

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6
Q

HLA DR3 (5)

A

Diabetes mellitus type 1, SLE, Graves disease, Hashimoto thyroiditis, Addison disease.

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7
Q

HLA DR4 (3)

A

Rheumatoid arthritis, diabetes mellitus type 1, Addison disease.

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8
Q

HLA DR5 (2)

A

Pernicious anemia -> vitamin B12 deficiency, Hashimoto thyroiditis

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9
Q

Hemochromatosis

A

HLA A3

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10
Q

Addison Disease (3)

A

HLA B8, HLA DR3/DR4

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11
Q

Myasthenia Gravis

A

HLA B8

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12
Q

Seronegative Arthropathies

A

HLA B27

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13
Q

Celiac Disease

A

HLA DQ2/DQ8

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14
Q

Multiple Sclerosis

A

HLA DR2

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15
Q

Hay Fever (Allergic Rhinitis)

A

HLA DR2

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16
Q

Systemic Lupus (2)

A

HLA DR2/DR3

17
Q

Goodpasture Syndrome

A

HLA DR2

18
Q

DM Type I (2)

A

HLA DR3/DR4

19
Q

Graves Disease

A

HLA DR3

20
Q

Hashimoto Thyroiditis (2)

A

HLA DR3/DR5

21
Q

Rheumatoid Arthritis

A

HLA DR4

22
Q

Pernicious Anemia

A

HLA DR5