Recognition Molecules Flashcards
What are the recognition molecules
MHC , TCR , Abs
What is MHC
A set of Surface molecules
Major part of immune system
Als called HLA
The main functions of MHC
1/Ag presentaion
2/donor compatibility for organ transplant
3/ determine susceptibility to autoimmune diseases
4/ forensic medicine
Classes of MHC
1,2,3
CD8 in Cytotoxic T cells recognize which class
MHC class1
CD4 in T helper cells recognize ..
MHC class2
What are TCR
Molecules found on surface of cells TCells responsible for recognition of antigenes on MHC
What are antibodies
Proteins produced by plasma cells to identify and neutralize pathogens
May be soluable or cell bound on BCells
Abs classes
GAMED
Which Ab can pass placenta
IgG
An Ab that triggers histamine release from mast cells and basophils
IgE
Ab that prtect body secretions
IgA
Ab trigger basophils and mast cells to produce anti microbial factors
IgD