receptors and their purpose Flashcards
describe what a receptor is
receptor = sensing elements of chemical communication within the body
describe the role of receptors in relation to therapeutic agents
many therapeutic agents act as agonists, antagonists or allosteric modulators of selected receptor types and can mimic, block, enhance or reduce the response of endogenous substances
describe the role of receptors in relation to ligand selectivity
due to ligand selectivity receptors can respond to one, or more signalling molecules in the extracellular or intracellular environment
what different types of molecules can target receptors
hormones, neurotransmitters and many more different kinds of signalling molecules(eg cytokines)
what are the 4 major types of receptor
ligand-gated ion channels(LGIC), G protein-coupled receptors(GPCR), Kinase linked receptors(aka enzyme linked), Nuclear receptors