Receptors

Question 1

List the QISS QIQ GPCR’s

Answer 1

A1- Q. A2- I. B1- S. B2- S. M1- Q. M2- I. M3- Q.

Question 2

Give an example of a B2 adrenorceptor agonist

Answer 2

Salbutamol, salmeterol

Question 3

Give an example of a B adrenoreceptor antagonist

Answer 3

Propranolol, Atenolol.

Question 4

Why will the effect of a parasympathetic, post ganglionic neurone be slower than one in the sympathetic NS?

Answer 4

Para has muscarinic receptors, Symp has nicotinic (LGIC). Muscarininc are GPCR’s which take longer to produce effect than ligand gated ion channels.

Question 5

List the receptor super families. Give examples.

Answer 5

Ligand gated ion channels (nicotinic ACh receptor). Receptors with intrinsic enzyme activity (insulin receptor). GPCR’s (muscarinic, beta rceptors)