receptors Flashcards
The heart has ____ cholinergic receptors
M2
Do blood vessels have cholinergic receptors?
Yes, they have M receptors, but they are not innervated
The heart has ___ adrenergic receptors
B1
The lungs have ___ adrenergic receptors
B2
The vessels have what adrenergic receptors?
a1 (vasoconstriction of splanchnic)
B2 ( vasodilation of vessels to skeletal muscle)
What are the two cholinergic responses of the eye?
Myosis ( contraction of pupil)
accommodation (near vision)
What are the two adrenergic responses of the eye?
mydriasis (dilation of pupil)
increased IOP from aqueous humor
GI cholinergic responses
increased secretion and increased motility
GI adrenergic responses
decreased motility, relaxation
genitourinary cholinergic responses
contraction of detrusor muscle, relax sphincter
genitourinary adrenergic responses
constrict sphincter, relax bladder, relax uterine contractions
Kidney adrenergic response
increase renin
GI adrenergic receptors
a2 B2-3
Kidney adrenergic receptors
B1
GU adrenergic receptors
A1, B2, B3
Adrenergic receptors in the eye
a1, B
Stimulation of a1 causes
CONTRACTION
- splanchnic vasoconstiction
- Mydriasis (dilate pupil)
- contraction of bladder sphincter
Stimulation of B1 causes
increased HR, AV conduction, increased renin secretion from the kidney
Stimulation of B2 causes
RELAXATION
- vasodilation of vessels feeding skeletal muscle
- bronchodilation
- GI relaxation
- relaxation of uterine muscle
- relaxation of bladder
a2 stimulation causes
decreased GI motility, inhibition of NE release in presynaptic membrane
Epinephrine adrenergic receptors
a1, B1, B2
Norepinephrine adrenergic receptors
a1, B1
Isoproterenol adrenergic receptors
B1, B2
Albuterol acts on which adrenergic receptors?
B2
Clonidine works on which adrenergic receptors?
a2
Dopamine works on which adrenergic receptors?
D1, indirect
Prazosin antagnoizes which adrenergic receptors?
a1
Doxazosin antagnoizes which adrenergic receptors?
a1
Terazosin antagnoizes which adrenergic receptors?
a1
The “-zosin”s work on which adrenergic receptors?
a1
Metoprolol antagnoizes which adrenergic receptors?
B1
Atenolol antagnoizes which adrenergic receptors?
B1
What are the “cardiac specific” Beta blockers?
Metoprolol and atenalol because they only antagonize B1, found in the heart
Propranalol antagnoizes which adrenergic receptors?
B1, B2
Labetalol antagnoizes which adrenergic receptors?
a1, B1, B2
Carvedilol antagnoizes which adrenergic receptors?
a1, B1, B2
