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Advanced Pharmacotherapeutics Exam 1 > Receptors > Flashcards

Receptors Flashcards

1
Q

CNS (muscarinic or nicotinic)

A

muscarinic (M1-M5) also nicotinic

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2
Q

secretory glands- salivary, stomach, sweat glands (muscarinic or nicotinic)

A

muscarinic

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3
Q

cardiac tissue (muscarinic or nicotinic)

A

muscarinic (M2)

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4
Q

smooth muscle (muscarinic or nicotinic)

A

muscarinic (M3)

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5
Q

parasympathetic system (muscarinic or nicotinic)

A

muscarinic
Remember PMS

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6
Q

neuromuscular junction (muscarinic or nicotinic)

A

nicotinic

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7
Q

autonomic ganglia (muscarinic or nicotinic)

A

nicotinic

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8
Q

adrenal medulla (muscarinic or nicotinic)

A

nicotinic

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9
Q

activation of nicotinic receptors leads to opening of?

A

K+ and Na+ channels

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10
Q

what does opening of K+ and Na+ channels lead to?

A

depolarization (nicotinic)

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11
Q

what do M1, M3, and M5 activate?

A

phospholipase C

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12
Q

what do M2 and M4 do?

A

inhibit adenylate cyclase and decrease Camp

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13
Q

what adrenergic receptor? Mydriasis/pupil dilation

A

alpha 1

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14
Q

what adrenergic receptor? Arterioles constrict

A

alpha 1

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15
Q

what adrenergic receptor? Veins constrict

A

alpha 1

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16
Q

what adrenergic receptor? Prostatic capsule contracts

A

alpha 1

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17
Q

what adrenergic receptor? Male ejaculation

A

alpha 1

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18
Q

what adrenergic receptor? Bladder contracts

A

alpha 1

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19
Q

what adrenergic receptor? Increased BP (vasoconstriction)

A

alpha 1

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20
Q

what adrenergic receptor? Increased peripheral vasoconstriction

A

alpha 1

21
Q

what adrenergic receptor? Increased HR

A

beta 1

22
Q

what adrenergic receptor? Increased contractility

A

beta 1

23
Q

what adrenergic receptor? Increased AV conduction velocity

A

beta 1

24
Q

what adrenergic receptor? Increased renal renin release

A

beta 1

25
Q

what adrenergic receptor? Increased lipolysis

A

beta 1

26
Q

what adrenergic receptor? Dilation of renal vasculature

A

dopamine

27
Q

what adrenergic receptor? Arteriole dilation- heart

A

beta 2

28
Q

what adrenergic receptor? Lung arteriole dilation

A

beta 2

29
Q

what adrenergic receptor? Arteriole dilation skeletal muscle

A

beta 2

30
Q

what adrenergic receptor? Uterine relaxes

A

beta 2
BAY BEES

31
Q

what adrenergic receptor? Liver- increased glycogenolysis

A

beta 2

32
Q

what adrenergic receptor? Skeletal muscle enhanced contraction

A

beta 2

33
Q

what adrenergic receptor? Increased skeletal muscle glycogenolysis

A

beta 2

34
Q

what adrenergic receptor? Vasodilation

A

beta 2

35
Q

what adrenergic receptor? Decreased peripheral resistance

A

beta 2

36
Q

what adrenergic receptor? Increased glucagon release

A

beta 2

37
Q

what adrenergic receptor? Relax uterine smooth muscle

A

beta 2

38
Q

what adrenergic receptor? Inhibits NE release

A

alpha 2

39
Q

what adrenergic receptor? Presynaptic nerve terminals

A

alpha 2

40
Q

what adrenergic receptor? Inhibits acetylcholine release

A

alpha 2

41
Q

what adrenergic receptor? Inhibits insulin release

A

alpha 2

42
Q

nicotinic or muscarinic? Contraction of skeletal muscle

A

nicotinic (M)

43
Q

muscarinic- effect on heart rate?

A

decreased heart rate

44
Q

muscarinic- effect on lungs?

A

bronchial constriction

45
Q

muscarininc- effect on bronchial secretion?

A

increased bronchial secretion

46
Q

muscarinic- effect on bladder?

A

contraction of detrusor

47
Q

muscarinic- effect on gastric secretion?

A

increased gastric secretion

48
Q

muscarininc- effect on intestinal tone and motility?

A

increased

49
Q

muscarinic- effect on sweat glands?

A

generalized sweating

Advanced Pharmacotherapeutics Exam 1 (4 decks)

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