Recap

Question 1

Iron deficiency anemia

Answer 1

Microcytic, hypochromic, non-regenerative, fragmentation morphologies, and 50 % of the time reactive thrombocytosis.

Look for chronic slow bleed (ie: upper GI tract)

Question 2

IMHA DX

Answer 2

Usually sever, very regenerative anemia with a lot polychormiatophils (reticulocytes-macrocytic and hypochromic), spherocytes, can have inflammatory leukogram, micr/macroagglutination, possibly ghost cells

Give prednisole and possibly blood transfusion IMMEDIATELY

Question 3

Anemia of chronic inflammatory dz

Answer 3

Mild, non-regenerative anemia

Normochromic, normocytic

VERY COMMON IN VET MED

Body sequesters iron to hide from bacteria

Question 4

Fragmentation morphologies

Answer 4

Keratocytes

acanthocytes

schistocytes

Question 5

In fragmentation morphology look for…

Answer 5

hemangiosarcoma

Iron deficiency anemai (look for RBC indices)

DIC

Liver disease

Question 6

Bilirubin

Answer 6

Breakdown product of hemoglobin

Metabolized by liver

accumulates and causes icterus in liver disease or increase lysis of RBCs

Question 7

Bilirubinemia

Answer 7

Can occur with intravascular AND extravascular hemolysis

Question 8

Hemoglobinemia

Answer 8

Indicator of intravascular hemolysis