Recalls Flashcards

1
Q

1) Non healing diabetic ulcer duration not remembered, both dorsalis pedis pulse are absent. Xray done showing osteomyelitis. Most appropriate investigation?
a. MRI
b. Arterial doppler study

A

ANSWER: B
Diagnosis: peripheral arterial occlusive disease - complication of DM that can develop into both non-healing ulcers and osteomyelitis.

Initial diagnostic tool is ABI, however Duplex/doppler ultrasound (B) is often the only imaging required to plan endovascular interventions. It is also the main investigation for follow up of vascular interventions

Source: RACGP Peripheral Arterial Disease

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2
Q

2) A 35 year old man went to pub, where a woman bit him, totally unknown and
she went away. 2 cm lesion, bleeding continues, teeth mark, he is fully tetanus immunized 3 years.
ago. What to do now?

A-suture and review in 24 hours
B-hep B vaccine and immunoglobulin
C- zidovudine
D- Azithromycin
E- tetanus immunoglobulin
A

Answer: B
Hepatitis B and C can be transmitted by human bites and human immunodeficiency virus (HIV) transmission has occurred on at least five occasions, mostly in the setting of bloody saliva and late stage HIV disease.

• For human bites consider hepatitis B prophylaxis if not immune and HIV postexposure prophylaxis if at high risk (seek advice from infectious diseases physician)
______

A - Primary closure could be considered in carefully selected bite wounds where cosmesis is an issue; suturing is not recommended in wounds at high risk of infection

C - HIV postexposure prophylaxis should be considered in high risk human bite injuries (ie. from a known HIV positive source).

D - Mammalian bite antibiotic guidelines:

E - Tetanus toxoid should be administered if 5 years since the last dose and the patient has completed a full primary course of tetanus immunisation. If the patient is unvaccinated, they should receive tetanus toxoid plus tetanus immunoglobulin

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3
Q
3) A patient with prostate ca T3b N0M0. Management
A.Radical prostatectomy
B.orchidectomy
C. External beam radiation therapy
D. Androgen deprivation
A

Best answer: B? (more specific than D?)

In this case, prostate CA stage T3b N0M0 describes a locally invasive disease spreading to the seminal vesicles.

MURTAGH (1076): For metastatic or locally advanced disease, androgen deprivation is the cornerstone of treatment, the options
being:
bilateral orchidectomy
or
daily anti-androgenic tablets, for example:
— cyproterone acetate (Androcur)
— flutamide (Eulexin)
— bicalutamide (Cosudex)
or
luteinising hormone releasing hormone (LHRH)
agonists: depot injections of LHRH analogues, for
example:
— goserelin (Zoladex)
— leuprorelin acetate (Lucrin, Eligard)

GUIDELINES:
Locally advanced prostate cancer (stage C)
It is questionable whether patients with locally advanced disease are able to be cured using currently available treatment. These men are not candidates for surgical resection and treatment is usually with radiotherapy or with hormonal ablation.

Bilateral orchidectomy is the gold standard for androgen ablation in men with prostate cancer. It results in a rapid and permanent decrease in circulating testosterone levels. A dramatic improvement in the symptoms of metastatic prostate cancer can occur within a few hours or days.

Note: ideal is combination of EBRT and Androgen Deprivation… so maybe the question is poor recall, and if the question was least appropriate management, the answer is A

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4
Q
4) Case of old woman with iron deficiency anemia, no symptoms, no complaints, cause?
A. Carcinoma of caecum
B. Carcinoma of.....
C. Carcinoma of stomach
D. nutritional deficiency
#Surgery #2018
A

Answer: A

Carcinoma of caecum and
ascending colon:

Malignancy in this area is more likely to present with
symptoms of anaemia without the patient noting obvious
blood in the faeces or alteration of bowel habit.

DxT: blood in stools + abdominal discomfort +
change in bowel habit = colon cancer

Source: Murtagh, (236, 265)

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5
Q

5) Drawing pentagon, which hemisphere test..with scenario
a. Fronto parietal
b. Dominant parietal
c. Occipital
d. temporal
e. Non dominant parietal
#Neurology #2018

A

Answer: E

The nondominant parietal lobe integrates the contralateral side of the body with its environment, enabling people to be aware of this environmental space, and is important for abilities such as drawing. Acute injury to the nondominant parietal lobe may cause neglect of the contralateral side (usually the left), resulting in decreased awareness of that part of the body, its environment, and any associated injury to that side (anosognosia). For example, patients with large right parietal lesions may deny the existence of left-sided paralysis. Patients with smaller lesions may lose the ability to do learned motor tasks (eg, dressing, other well-learned activities)—a spatial-manual deficit called apraxia.
_________

A - frontal cortex: Behavioral changes, primary motor area, Broca’s area

B - Dominant parietal: primary somatosensory area. Calculation, writing, left-right orientation, and finger recognition (Gertsmann syndrome)

C - occipital: cortical blindness; in one form, called Anton syndrome, patients become unable to recognize objects by sight and are generally unaware of their deficits

D - temporal: auditory perception, receptive components of language, visual memory, declarative (factual) memory, and emotion

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6
Q
6) 17 year old boy says he must count till 20 otherwise his mom will be killed. They had a minor accident 3 months ago. Boys keeping himself in the room most of the time. He is hearing voices but could not recognize them. What is the diagnosis?
A. OCD
B. Major Depression
C. Schizophreniform Disorder
D. PTSD
A

Best Answer: C

Symptoms: command hallucinations, auditory hallucinations. No No mood symptoms (rule out B), no anxiety or panic attack symptoms (rule out D).

The symptom profile of a schizophreniform disorder is identical to that of schizophrenia; however, the total duration of illness, including prodromal or residual phases, must be less than 6 months.

SOURCE

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7
Q

Swelling on anterior neck, lateral

Asking what will you find on physical examination

A palpable hard nodule under tongue
B movement on swallowing
C movement on tongue protrusion

A

Best answer: A

The picture attached is that of a branchial cleft cyst, a lateral neck mass not movable with deglutition, along the anterior border of the SCM. However, none of the given choices are consistent with a diagnosis of a branchial cleft cyst. Both b and c are features of a thyroglossal duct cyst, usually presenting as a midline neck mass.

A ranula can present as a small lateral neck mass, in the submandibular area, presenting with a palpable nodule under the tongue. This is the most likely answer (prob. with poor recall of the image)

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8
Q

8) Picture of facial palsy 1 day and ear discharge for 2 days, asking treatment?
Steroid
Famcyclovir

A

ANSWER: Neither
Both Otitis media and Otitis externa (swimmer’s ear) can develop facial palsy. Bell’s Palsy is a diagnosis of exclusion, Ramsay-Hunt syndrome, caused by the VZV usually presents with a painful ear rash, not ear discharge.

Treatment: bilateral myringotomy, antibiotic treatment, decongestants.

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9
Q
9) HSP scenario with leg photo, developed rash in buttock and leg, next investigation
A) abdominal USG
B) urinary phase-contrast microscopy
C) blood culture
D) CXR
#Medicine #2018
A

ANSWER: B
Urinalysis is usually the only investigation needed in a classic presentation of HSP
If there is hypertension, macroscopic haematuria or significant proteinuria:
● Formal urine microscopy and urinary protein-creatinine ratio (UPCR)
● Bloods for urea/electrolytes/creatinine (UEC) and albumin
In some instances further investigations may be required to rule out differentials if the diagnosis is unclear eg ITP, leukaemia, or to identify potential complications of HSP.
These may include:
● FBE, UEC, albumin
● Blood and urine culture
● Abdominal imaging
● ANA, dsDNA, ANCA, C3/C4 if significant renal involvement with an unclear diagnosis

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10
Q

10) Ankylosing spondylitis x-ray. Paracetamol, codeine taken but not improved
a. Indomethacin
b. prednisolone
c. Methotrexate
d. Infliximab

(no naproxen in option)

A

Answer: A
MURTAGH (347): Ankylosing spondylitis usually presents with an insidious onset of inflammatory back and buttock pain (sacroiliac joints and spine) and stiffness in young adults (age <40 years), and 20% present with peripheral joint involvement before the onset of back pain. It usually
affects the girdle joints (hips and shoulders), knees
or ankles. At some stage over 35% have joints other
than the spine affected. The symptoms are responsive
to NSAIDs

AS X-ray: Lumbar spine changes A) Shiny corners and erosions. B) Early syndesmophytes C) Spinal fusion or ankylosis

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11
Q

11) A female patient comes to you for medical check-up. You notice she has bruises and cuts on her limbs with a swollen left eye. She looks frightened and tells you that she does not want to go home. What do you do next?
A. Advise her to go home
B. Call her husband and counsel him
C. Refer to domestic violence (center?)
D. Admit her to hospital
E. Tell her to call relatives and stay with them

A

ANSWER: C

● High suspicion of intimate partner violence
● General practitioners can refer patients to local community legal centres, women’s legal services, legal aid and court support services.
● Joint counselling is not recommended and specific counselling needs to be by professionals trained in abuse and violence

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12
Q

24 years old lady with history of smoking otherwise healthy, BMI 35, taking OCP. Her mother was diagnosed with breast cancer at the age 75. She is not complaining of any breast lump. Came to you for advice regarding breast carcinoma. What will be your advice for her?

a) Quit smoking
b) Reduce weight
c) Stop OCP
d) Do self breast examination
e) Mammography annually

A

ANSWER: B

MURTAGH (953)
● Risk factors include increasing age (>40 years), Caucasian race, pre-existing benign breast lumps, alcohol, HRT >5 years, personal history of breast cancer, family history in a first-degree relative (raises risk about threefold), nulliparity, late menopause (after 53), obesity, childless until after 30 years of age, early menarche, ionising radiation exposure.
● Regular BSE is recommended for all women 35 years and over.
● Regular screening mammography after 50 years of age—every 2 years

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13
Q
13) 50 year old male presents with recurrent ca oxalate stones... Treatment?
Hydrochlorthiazide
Spironolactone
Decrease Ca
Decrease salt
Allopurinol
A

Answer: D
MURTAGH (323)
Recurrent urinary calculi
The dietary advice for recurrent urinary calculi includes:
1 Drink at least 2 L of water every day, or more if there is
increased fluid loss: this is the most important step.

2 Minimise consumption of foods that contain oxalate or uric acid. Foods that contain oxalate include:
• chocolate
• coffee
• cola drinks
• rhubarb
• tea
Foods that contain uric acid include:
• beer
• red wine
• red meat
• organ meats

3 Avoid milk in tea—calcium precipitates oxalate.

4 Avoid processed meats, organ meats (e.g. brain,
kidney, liver and sweetbread), yeast spreads and other
high-salt foods. Restrict salt intake.

5 Reduce animal protein consumption: restriction to one
major meat meal a day (includes chicken and fish).

6 Add citrate-containing fruit juices to the diet, including
grapefruit, apple and orange juice.

7 Eat a healthy diet of vegetables and fruit with a high fibre content.

GUIDELINES:
Patients with calcium oxalate stones, which are the most common,should be further advised to keep a low oxalate diet. The majority of published evidence now favours dietary salt and oxalate reduction rather than calcium reduction in these patients. The evidence in favour of salt reduction is strongest for patients with hypercalciuria. Common oxalate rich foods include: tea, chocolate, spinach, beetroot, rhubarb, peanuts, cola, and vitamin C (most supplementary vitamin C is converted to oxalate).

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14
Q
1) A 15-year-old girl presents with a palpable purpuric rash over her lower limbs accompanied by polyarthralgia following a recent sore throat. What is the most likely diagnosis?
A. Rubella
B. Measles
C. Erythema multiforme
D. Idiopathic thrombocytopenic purpura
E. Henoch-Schonlein purpura
A

Answer: E

HSP is characterised by palpable purpura with arthritis/arthralgia (~50-75%), abdominal pain (~50%) and/or renal involvement (~25-50%) (haematuria/proteinuria/hypertension). In ~50% of cases there is a history of a recent upper respiratory tract infection.

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15
Q
2) Patient comes for vaccination for cervical cancer. LSIL on pap 6 months ago. Today pap is taken again for testing. what advise for hpv vaccines??
a No need
Depends on hpv serology result
c Depends on hpv culture result
d vaccines now
e depend on today’s pap result
A

Answer: D (?)
● Women with a history of previous HPV infection will most likely benefit from protection against disease caused by the other HPV vaccine genotypes with which they have not been infected.
● The vaccine can be given to patients with previous cervical intraepithelial neoplasia, but practitioners need to emphasise that the benefits will be limited to future HPV exposure. Cervical cytology screening and corresponding management based on NHMRC and RANZCOG recommendations must continue

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16
Q
3) 8 year old boy presents with dysphagia to both solid and liquid foods for 1 month. His brother is a known case of asthma well controlled by salbutamol. o/e chest clear. What is the next investigation to reach diagnosis?
ct scan thorax
spirometry
chest xray
barium swallow
A

ANSWER: D
MURTAGH (510):
Any disease or abnormality affecting the tongue,
pharynx or oesophagus can cause dysphagia.
• Patients experience a sensation of obstruction at a
definite level with swallowing food or water; hence, it is
convenient to subdivide dysphagia into oropharyngeal
and oesophageal.
• Pain from the oropharynx is localised to the neck.
• Pain from the oesophagus is usually felt over the T2–6
area of the chest.
• Oropharyngeal causes: difficulty initiating swallowing;
food sticks at the suprasternal notch level; regurgitation; aspiration.
• Oesophageal causes: food sticks to mid to lower
sternal level; pain on swallowing solid foods,
especially meat, potatoes and bread, and then
eventually liquids.
• A pharyngeal pouch usually causes regurgitation of
undigested food and gurgling may be audible over the
side of the neck.
• Neurological disorders typically result in difficulty
swallowing or coughing or choking due to food
spillover, especially with liquids.
• Dysphagia for solids only indicates a structural lesion,
such as a stricture or tumour.
• Dysphagia for liquids and solids is typical of an
oesophageal motility disorder, namely achalasia.

The primary investigation in suspected pharyngeal
dysphagia is a video barium swallow, while endoscopy
is generally the first investigation in cases of suspected
oesophageal dysphagia. Barium swallow should precede
endoscopy in the latter when there is a suspected
oesophageal ‘ring’ and suspected oesophageal dysmotility.

17
Q
4) Gloves and stocking paraesthesia, difficulty in walking upstairs, decreased tone in both the lower limbs, reflexes are increased in 55y/m of one month duration. There is no prodrome of urti. Asked investigation to reach diagnosis?
mri spine
ct head
lumbar puncture
nerve conduction studies
A

Answer: D

Alcohol neuropathy - characterized by paresthesias (decreased pain and temperature sensation in a stocking-glove distribution), pain, and weakness, especially in the feet but extending proximally to the arms, causing difficulty in climbing stairs and walking.

Paresthesia and peripheral neuropathy RACGP guidelines:
Neurophysiology, using nerve conduction studies and electromyography, may be required, especially for the patient who proves to be a very poor historian or in whom confirmation of a diagnosis may dictate altered therapy.

18
Q
5) History of rash after penicillin injection. Asked what next antibiotic?
cephalexin
ciprofloxacin
roxithrtomycin
ticarcillin
A

Answer: A
Macular, papular, or morbilliform rashes occurring several days after commencement of treatment are more common than immediate reactions, and may be caused by the infection or its treatment. Such reactions are usually T-cell (not IgE) mediated. An immediate (IgE-mediated) reaction is characterised by the development of urticaria, angioedema, bronchospasm or anaphylaxis within one to two hours of drug administration.

19
Q
6) Man with scenario of claudication in left calf. On exam, all peripheral pulses palpable on right side. Left side all pulses palpable but dorsalis pedis weak and hardly palpable. Bilateral weakness of ankle reflex and loss of sensation in foot. ABI on right side 1, left side 0.75. Appropriate investigation?
A. Conventional angiogram
B. CT angiogram
C. CT spine
D. EMG
E. Arterial Doppler
A

ANSWER: E (?)
● Initial diagnostic tool is ABI, however Duplex/doppler ultrasound is often the only imaging required to plan endovascular interventions. It is also the main investigation for follow up of vascular interventions

● Detailed anatomic imaging is not necessary if endovascular or open surgical intervention is not planned

● Endovascular or surgical interventions are usually considered for lifestyle limiting intermittent claudication not responding to conservative therapies, and for critical limb ischaemia. (**If scenario is lifestyle limiting, answer is B prior to surgical intervention)

20
Q

7) A young lady is on sertraline for depression, but she wants to use ecstasy as a recreational drug on occasion. She asks your view and what is best?
a. Ecstasy and sertraline are agonists
b. Ecstasy is contraindicated when on sertraline
c. Sertraline and ecstasy have to have at least 24 h between each other
d. Ecstasy will antagonise sertraline’s effect shouldn’t be taken together
e. no harm taking ecstasy and sertraline together

A

Answer: A
● The primary mode of action of MDMA is as an indirect serotonergic agonist, increasing the amount of serotonin released into the synapse. MDMA acts on the serotonin transporter and is transported into the nerve terminal. This promotes release of serotonin through the serotonin transporter by a process of transporter-mediated exchange. Whilst within the terminal, MDMA interferes with the storage of serotonin within the vesicles and thus increases the amount of serotonin available to be released. This process can lead to significant increases in serotonin available in the synapse.

● Serotonin toxicity may occur in combination with antidepressants

● MDMA, in combination with the widely-prescribed SSRI antidepressant class, can lead to rapid, synergistic rise of serotonin (5-HT) concentration in the central nervous system, leading to the acute medical emergency known as serotonin syndrome