Reasons for Association 1 Flashcards

1
Q

Association

A

Link between two variables (exposure and outcome)

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2
Q

Causation

A

Relationship between cause and effect

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3
Q

Bradford-Hill’s criteria for assessing causation

A
Strength of association
Consistency
Specificity
Temporality
Biological gradient 
Biological plausibility
Coherence
Experiment 
Analogy
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4
Q

Strength of association

A

High association between risk and outcome, more likely to be causal

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5
Q

Consistency

A

Same in different populations, study designs, times etc

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6
Q

Specificity

A

One to one relationship (uncommon in reality)

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7
Q

Temporality

A

Exposure must precede outcome

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8
Q

Biological gradient

A

Change in intensity of exposure = change in risk of outcome

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9
Q

Biological plausibility

A

Potential bio mechanism to explain

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10
Q

Coherence

A

Relationship found agrees with current knowledge

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11
Q

Experiment

A

Removal of exposure alters frequency of outcome

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12
Q

Analogy

A

Relationship is in line with other established cause-effect relationships

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