Reagents and conditions Flashcards
Carboxylic acid to Ester
Alcohol/conc H2SO4
Acyl chloride to carboxylic acid
RCOCl
H2O
Alkene to alcohol
Steam
H3PO4 catalyst
300 degrees C
60-70 atmospheres
Acyl chloride to secondary amide
RNHCOR’
Primary amiNe
Acyl chloride to Ester
Alcohol
Ketone to hydroxynitrile
NaCN(aq)/H+(aq)
Alkane to haloalkane
X2 (where X is a halogen)
UV light
Secondary alcohol to ketone
K2Cr2O7/H2SO4 (acidified potassium dichromate)
Reflux
Ester to carboxylic acid
Dilute acid, heat
Nitrile to amine
H2/Ni
Hydroxynitrile to amine
CN triple bond with an OH group
H2/Ni
Aldehyde to primary alcohol
NaBH4
Haloalkane to amine
(R-NH2) or secondary + tertiary version
NH3/ethanol
Ketone to secondary alcohol
NaBH4
Aldehyde to carboxylic acid
Or primary alcohol to carboxylic acid
K2Cr2O7/H2SO4 (acidified potassium dichromate)
Reflux
Hydroxynitrile to carboxylic acid
H2O/HCl, heat
Alcohol to Ester
Carboxylic acid/H2SO4
Or
Acid anhydride
Alcohol to an alkene
Add conc.H2SO4 or H3PO4
Heat
Haloalkane to alcohol
Warm NaOH or KOH
H2O
Reflux
Alkene to dihaloalkane
X2 (X is a halogen)
20 degrees C
Dihaloalkane as you’re adding 2 halogen atoms to the molecule
Alkene to alkane
H2
Nickel catalyst
150 degrees C/423K
Aldehyde to hydroxynitrile
NaCN(aq)/H+(aq)
Nitrile to carboxylic acid
H2O/HCl, heat
Acyl chloride to primary amide
RCOCl) (RCONH2
NH3
Ester to carboxylate (RCOO-)
OH-, heat
Primary alcohol to aldehyde
K2Cr2O7/H2SO4 (acidified potassium dichromate)
Distillation
Haloalkane to nitrile
CN triple bond
CN-/ethanol
Carboxylic acid to acyl chloride
RCOCl
SOCl2
Alkene to haloalkane
HX (where X is a halogen)
20 degrees C
Alcohol to haloalkane
NaX
H2SO4 catalyst
20 degrees C
Can be done with any compounds containing halide ions