Readings Flashcards
What are the determinants of TB in aboriginal people of Canada?
What programmatic factor could be improved to address TB in aboriginal people?
In Canada, the incidence rate of TB is higher among Aboriginal people than the foreign-born and Canadian-born non-Aboriginals, but the greatest burden of disease, as measured by the number of cases, occurs in the foreign-born.
Status Indians in Manitoba and Saskatchewan and the Inuit in Nunavut have the highest incidence rates among Aboriginals in Canada.
In the 1980s, after decades of decline, the incidence of TB among the Inuit began to level off. However, beginning in the late 1990s and continuing until 2010, rates increased, resulting in Canada’s own “U-shaped curve of concern”.
Determinants of TB infection and disease in the Aboriginal people of Canada differ with respect to comorbidities, genetic factors, transmission factors and the social determinants of health when compared to the rest of Canada.
Social determinants of health, including lack of food security, housing, health care access, education and income are seen with higher frequency in Aboriginal groups in Canada.
Programmatic issues in TB prevention in Aboriginal groups in Canada that can be strengthened include strong TB partnerships with communities, increased community awareness, improving adherence to TB medications and underscoring the importance of effective contact investigation.
According to the most recent statistics released in 2012, the current rate of TB among the Canadian-born Aboriginal population is 26.4 per 100,000. Across Canada rates of new active and retreatment TB cases for the Aboriginal population were as follows: North American Indian 22.2 per 100,000 (188 cases), Inuit 198.6 per 100,000 (116 cases) and Métis 7.5 per 100,000 (26 cases).
In 2005, FNIHB set a long-term goal to reduce TB incidence to 3.6 per 100,000 among on-reserve First Nations and Inuit regions in Canada by 2015. Results to date suggest that this goal will not be met.
To meet these goals and achieve a substantial reduction in rates of TB among Canadian-born Aboriginal peoples it seems likely that intensified and coordinated efforts using novel approaches will be necessary.
What are Canadian guidelines around HCW infected with HBV, HCV or HIV?
Guideline recommendations: HIV, HCV and HBV
The following recommendations are common to HCWs infected
with any of the three BBVs (refer to the Guideline for full context
and footnotes on these):
• All HCWs who perform exposure-prone procedures have
ethical and professional obligations to know their HIV/HCV/
HBV status
oo If their status is negative, the HCWs should be tested
at appropriate intervals: as determined by their level of
risk and whenever an exposure has occurred
• HCWs infected with HIV/HCV/HBV who do not perform
exposure-prone procedures do not need any restrictions on
practice based on their BBV status alone
• If a HCW-to-patient transmission of HIV/HCV/HBV occurs,
the HCW should cease clinical practice immediately until
determination for fitness to return to practice is made
Table 2: Recommendations for management of
healthcare workers infected with HIV
Recommendations
HCWs infected with HIV should _seek medical care from a physician
with expertise in HIV management for optimal health maintenanc_e
and should be managed according to current recommendations with
regular monitoring of HIV RNA levels.
HCWs infected with HIV should be restricted from performing
exposure-prone procedures until:
• the HCW is under the care of a physician with expertise in HIV
management; and
• the HCW is either on effective combination antiretroviral therapy or
has been identified as an elite controller; and
• the HCW’s viral load is undetectablea.
HCWs infected with HIV who are on effective combination antiretroviral
therapy (or are elite controllers), and have an undetectable viral load
should have no restrictions on practice based on HIV status alone.
Recommendations for management of
healthcare workers infected with hepatitis C virus
Recommendations
Confirmation of active HCV infection should be done using HCV
RNA testing. HCWs infected with HCV should seek medical care
from a physician with expertise in HCV management for optimal
health maintenance and should be managed according to current
recommendations.
HCWs testing positive for HCV RNA should be restricted from
performing exposure-prone procedures until:
• the HCW is under the care of a physician with expertise in HCV
management; and
• the HCW has completed effective therapya,b; and
• the HCW has tested negative for HCV RNA at least 12 weeks
post‑treatmentb.
Note: Expert Review Panels may individualize practice restrictions to
allow a HCW to perform exposure-prone procedures while on effective
therapy provided the virus is undetectable. The HCW’s practice should
then be restricted post treatment until a sustained virologic response
is confirmed.
HCWs testing negative for HCV RNA 12 weeks post-treatment can be
considered to have a sustained virologic response and should have no
restrictions on practice based on HCV status alone.
Recommendations for management of
healthcare workers infected with hepatitis B virus
Recommendations
HCWs who remain susceptible to HBV (anti-HBs negative and anti-HBc
negative) should be tested at appropriate intervals as determined by
their level of risk and whenever an exposure has occurred.
HCWs born or previously residing in high HBV endemic countries
should be tested for both anti-HBc and HBsAg to fully define HBV
statusa,b.
HCWs infected with HBV should seek medical care from a physician
with expertise in HBV management for optimal health maintenance
and should be managed according to current recommendations with
regular monitoring of HBV DNA levelc.
_HCWs infected with HBV should be restricted from performing
exposure-prone procedures until:
• the HCW is under the care of a physician with expertise in HBV
management; and
• the HCW’s HBV DNA level is below 103 IU/mL (5 x 103 GE/mL)d or
equivalent and monitored regularly (every 3 to 6 months)_e.
HCWs infected with HBV who have HBV DNA levels less than or equal
to 103 IU/mL (5 x 103 GE/mL)d or equivalent should have no restrictions
on practice based on HBV status alone.
What are health consequences of UV exposure?
basal cell carcinoma
squamous cell carcinoma
melanoma
premature aging of skin
cataracts
may suppress cell-mediated immunity
What are the 8 domains of Age-Friendly Cities Project?
In 2006, the World Health Organization (WHO) developed the Global Age-Friendly Cities Project. This project brought together cities from around the world that were interested in supporting healthy aging by becoming more age-friendly. These cities gathered information from seniors, senior-care providers and other groups and individuals with an interest in age-friendly communities. This information helped to identify eight key domains of community life in which communities can become more age-friendly. These domains are:
outdoor spaces and buildings;
transportation;
housing;
social participation;
respect and social inclusion;
civic participation and employment;
communication and information; and
community support and health services.
What are key elements that should be included in job descriptions
Exact title and status (part-time or full-time, permanent or time-limited)
Salient details regarding the job (geographical location, salary, shiftwork, etc.)
Description of core functions/competencies
Prerequisites/requirements (education, professional memberships, experience, language, etc.)
What is forecasting
A method of estimating what may happen in the future that relies on extrapolation of existing trends.
What are evidence-based interventions to modify physician behavior?
audit and feedback,
computerized decision support systems,
continuing medical education,
financial incentives,
local opinion leaders,
marketing / academic detailing
patient-mediated interventions,
reminders, and
multifaceted interventions
Define and contrast impairment, disability and handicap
Impairment
A loss of function or ability
Disability
Functional limitation due to an impairment
Handicap
A condition imposed on a person with disabilities by society, the physical environment, or the person’s attitude
According to the Canadian pandemic plan, what are factors that affect the potential impact of a pandemic?
Virus transmissibility - degree of transmission, speed of spread, season of arrival.
Virulence - clinical severity
Population vulnerability - pre-existing population immunity, unexpected risk factors, special groups and settings
Public health interventions - vaccine (availability, timing, effectiveness), antiviral (availability, resistance), PHSM
Health care system response - access to care, surge capacity, supply availability
Risk communication - behavioral response
What are strategies to reduce childhood obesity according to PHAC in 2012?
Vision: Canada is a country that creates and maintains the conditions for healthy weights so that children can have the healthiest possible lives.
This Framework for Action is comprised of three integrated strategies:
I—Making childhood overweight and obesity a collective priority
for action for F/P/T Ministers of Health and/or Health
Promotion/Healthy Living, who will champion this issue and
encourage shared leadership and joint and/or complementary
action from government departments and other sectors of
Canadian society.
II—Coordinating efforts on three key policy priorities:
> Supportive Environments: making social and physical
environments where children live, learn and play more
supportive of physical activity and healthy eating;
> Early Action: identifying the risk of overweight and obesity
in children and addressing it early; and,
> Nutritious Foods: looking at ways to increase the availability
and accessibility of nutritious foods and decrease the
marketing of foods and beverages high in fat, sugar and/
or sodium to children.
III—Measuring and reporting on collective progress in reducing
childhood overweight and obesity, learning from successful
initiatives, and modifying approaches as appropriate.
Strategies
Evidence shows that childhood overweight and obesity can be
infl uenced by several important factors, including:
> the availability and affordability of nutritious food;
> the accessibility of proper nutrition and support to
mothers during pregnancy;
> the provision of baby-friendly health settings;
> the protection of children from the marketing of foods
and beverages high in fat, sugar and/or sodium;
> the levels of physical activity and healthy eating within
the school environment;
> the early identification of infants and children who are
overweight or obese and referral to an eff ective child
healthy weight program;
> the supportive design of communities to encourage
active living;
> the levels of awareness, skills and knowledge of
Canadians, including parents and caregivers, regarding
the importance of healthy eating and physical activity;
> the need for children and their families to have positive
mental health and have access to community or public
health services.
What are Brighton anaphylaxis criteria?
sudden onset
rapid progression
2+ organ systems:
- at least one major cardiovascular or resp criterion +
- one major derm
+ culpable exposure
+ no alternate explanation
What are the messages to general and at risk population depending on the AQHI levels?
What are criticisms of the AQHI?
AQHI Criticisms
Not validated for rural regions
Most health effects are from long term exposure yet unknown relationship with chronic exposure
Most people spend their time inside, more exposure inside
Doesn’t account for other pollutants (only PM2.5, O3, NO2)
Assumes additive effect
Limited evidence on benefits from messaging
Does not include heat, humidity, allergens
Community average
In the F/P/T public health response plan for biological events, what are the response levels and response goals?
Response levels: routine, heightened, escalated, emergency
Response goals: Outbreak prevention, outbreak control, risk mitigation, mitigate impact/social disruption
- *Normal or routine**
- Info sharing bw jurisdiction and other FPTI authorities
- *Heightened**
- Routine PH response involving one or more jurisdictions
- *Escalated**
- Coordinated FPT response as it is one of:
- An event in multiple jurisdictions within Canada and unusual in progression/severity
- PHEIC occurring outside of Canada
- Potential implications for Canadian HC system
- Potentially require provision of aid
- *Emergency**
- Coordinated FPT response as it is one of:
- Event in Canada causing significant illness w potential for rapid spread
- Risk in Canada has potential for causing significant illness and/or could spread internationally from Canada
- PHEIC that could cause significant illness within Canada
What are the incubation period, PEP and contagious period for vaccine preventable diseases?
Hepatitis A
Incubation: 15-50d - usually 28-30
PEP:
- within 2 weeks,
- <6 months → Ig alone;
- immunocompromised, age>60 years, or liver disease → vaccine + Ig;
- all other contacts → vaccine alone;
Contagiousness: 2 weeks before clinical illness to 7 days after the onset of jaundice
Measles
Incubation: 7-21d (avg 10 to fever, 14 to rash)
PEP:
- >12months vaccine within 72h,
- 6-12mo vaccine within 72h or Ig 3-6d,
- <6mo/IC/preg Ig within 6d
Contagiousness: 4 days before to 4 days after rash onset
Mumps
Incubation: 12-25d (avg 16-18)
PEP: none (vaccinate for future exposures)
Contagiousness: 2 days before to 5 days after parotitis onset
Rubella
Incubation: 14-21d (avg 14-17)
PEP: Ig may be considered in pregnancy if would not consider abortion; test those in first trimester after exposure (IgM/IgG), vaccinate for future exposures
Contagiousness: 1 week before rash to 4 days after
Varicella
Incubation: 10-21d (avg 14-16)
PEP: vacc within 72h, IG if high risk and can’t vacc
Contagiousness: 5 days before rash until all lesions are crusted
Meningococcal disease
Incubation: 2-10d (avg 3-4)
PEP: abx for close contacts (cipro/CTX/rif), strain-specific vaccine for those with ongoing exposures
Contagiousness: 7 days before symptoms to 24h after initiation of antibiotics
Pertussis
Incubation: 6-20d (avg 9-10)
PEP: macrolide for households contacts within 21 dayswhere there is:
- a child <1y ,
- pregnant person
- high-risk contacts
Contagiousness: No longer contagious 5 days after antibiotics.
Haemophilus influenzae
Incubation: Unknown, probably 2-4d
PEP: rifampin for all unimmunized or incompletely
immunized household and child care contacts
Diphtheria
Incubation: 2-5d, occasionally longer
PEP: PCN (IM) or erythro for all close contacts regardless of immunization status; vacc for underimmunized or if >5y from last dose
Tetanus
Incubation: Months to years
PEP (wound mgmt):
- clean/minor - vaccine if underimmunized, vaccine if last dose >10y;
- dirty/major - vacc & IG if underimmunized, vaccine if last dose >5y
Influenza
Incubation: 1-4d (avg 2)
PEP: oseltamivir x 5d for high risk people
Contagiousness: 24h before illness onset to 7 days after
Hepatitis B
Incubation: 45-180d (avg 60-90)
PEP:
- infants born to infected mothers -> vaccine within 12h and HBIG, then vaccine at 1-2 and 6 mos
- susceptible person potentially exposed to infected bodily fluid (bite, sexual activity, needlestick, sharing IVDU equipment) ->
HBIG if known exposure and non immune/status unknown, vaccine series;
if immune with titres >10 milliIUs/mL no treatment.
- suseptible house household or sexual contacts of acute or chronic carrier case needlestick -> vaccinate
Polio
Incubation: 3-35d (avg 7-14d)
PEP: aggressive community immunization
Pneumococcal disease
Incubation: Unclear, may be as short as 1-3d or associated w colonization
No PEP
Order of vaccine: Conjugate vaccine before polysaccharide in older adults (1 mo wait, otherwise have to wait a year)
What are recent trends in STBBI in Canada?
Concerning increases for some sexually transmitted
and blood-borne infections (STBBI) have been
observed in Canada. From 2007 to 2016, the
reported rates for chlamydia, gonorrhea, and
syphilis increased by 49%, 81% and 178%,
respectively (Figure 5).38 Moreover, six cases of
congenital syphilis were reported in Canada in
2015, reversing the previous downward trend
observed from 2011 to 2014.39 This result is disquieting
as it coincides with a rise in syphilis cases
in women of childbearing age. There are numerous
factors that may contribute to some extent to the observed trends, o_ther than a true rise in incidence,
such as improved diagnostic tools, contact tracing,
and case detection_.40
While the number of newly diagnosed HIV infections
remained relatively stable in Canada_, 14% of people
living with HIV were estimated to be unaware of
their status in 2016_.41 Similarly, as of 2016, national
Hepatitis C infection rates remained stable over the
course of previous years.42 An estimated 44% of
Canadians living with Hepatitis C are thought to be
unaware of their status.43
Some communities are disproportionally affected.
For example, g_ay, bisexual and other men who
have sex with men accounted for more than 50%
of new HIV infections in 2016, although they represented
approximately 3% of the male population_in
Canada. Indigenous peoples accounted for 11% of
new HIV infections in 2016, but represented only
5% of the general population.41
Certain sub-populations are at high risk for
Hepatitis C infections, such as people who
inject drugs and people who are incarcerated.
Define AEFI.
What AEFI should be reported?
What are 5 classifications for AEFIs?
An AEFI is any untoward medical occurrence which follows immunization and which does not necessarily have a causal relationship with the usage of the vaccine. The adverse event may be any unfavourable or unintended sign, abnormal laboratory finding, symptom or disease.
AEFIs should be reported when the event:
Has a temporal association with a vaccine;
Has no other clear cause at the time of reporting: A causal relationship between immunization and the event that follows does not need to be proven and submitting a report does not imply or establish causality. Sometimes the vaccinee’s medical history, recent disease, concurrent illness/condition and/or concomitant medication(s) can explain the event(s).
Of particular interest are those AEFIs which:
Meet one or more of the seriousness criteria: An adverse event that is life threatening or results in death, requires hospitalization or prolongation of an existing hospitalization, results in residual disability or causes congenital malformation.
Are unexpected regardless of seriousness: An adverse reaction whose nature, severity, or outcome is not consistent with the term or description used in the local/regional product labeling (e.g., Package Insert or Summary of Product Characteristics) should be considered unexpected.
AEFIs are grouped into five categories (PHO):
Vaccine product-related reaction
Vaccine quality defect-related reaction
Immunization error-related reaction
Immunization anxiety-related reaction
Coincidental event
What are criteria for deciding on health indicators?
Address important issues
Feasible
Scientifically valid
Implications are understood
Provide meaningful information
Single measure
Reported regularly
Relevant and actionable info
Provides comparable info
Tracks progress and performance over time
How to calculate chi-square statistics?
What is NACI’s framework for systematically considering vaccine program recommendations?
NACI’s Framework for for the systematic consideration of ethics, equity, feasibility, and acceptability in vaccine program recommendations
ESSENTIALLY:
Conduct reviews of scientific factors
Then apply EEFA matrices: ethics, equity, feasibility, acceptability
Consult as needed
What types of data are collected in the Canadian Community Health Survey?
How are the results of the Canadian Community Health Survey used?
Participants will be asked questions on multiple topics such as the perception of their physical and mental health state, on chronic conditions, the use of health care services, and behaviors related to health such as smoking, physical activity, consumption of fruits and vegetables and alcohol use.
Data are also collected on a variety of socio-demographics. These data allow for health analysis for specific population groups (by age groups, geography, etc.)
By collecting information about health at the community level, the Canadian Community Health Survey can support:
program design and evaluation
health needs assessments
policy development
advocacy
research
support local health units by providing them with the timely information they need to evaluate existing programs and to design new ones suited to their communities
provide more current, detailed and uniform health information in every province and territory.
Results of our surveys are used for policy-making and program development that affect Canadian communities. The Canadian Community Health Survey has already been instrumental in drawing attention to emerging health issues, such as the decrease in teen smoking.
Your information may also be used by Statistics Canada for other statistical and research purposes.
What are requirements for optimal childhood development?
What is the early development index and what are its 5 domains?
Requirements for optimal childhood development
Time and commitment
Financial resources
Psychological resources
Institutional resources
Skills and knowledge
Good nutrition
Safe and supportive physical environments
Stable and responsive relationships
The Early Development Instrument, or the EDI for short, is a questionnaire developed by Dr. Dan Offord and Dr. Magdalena Janus at the Offord Centre for Child Studies at McMaster University.
The EDI is a 103-item questionnaire completed by kindergarten teachers in the second half of the school year that measures children’s ability to meet age-appropriate developmental expectations in five general domains:
Physical health and wellbeing
Language and cognitive development
Emotional maturity
Social competence
Communication skills and general knowledge
What are drivers of program implementation?
What are types of budget?
Master budget
Operating budget (expense and revenue)
Cash flow budget
Financial budget
Static or forecasting budget
Mnemonic Finance Master Cash Operation
What are the key areas of focus in the TB federal framework?
I. Optimizing and enhancing current efforts to
prevent and control active TB disease
II. Facilitating the identification and treatment
of latent TB infection for those at high risk
of developing active TB disease
III. Championing collaborative action to address
the underlying risk factors for TB (SDoH)
