reactive oxygen species Flashcards
1
Q
what vitamins are anti oxidants
A
C and E
C: high conc in cells, maintained in reduced state by GSH reactions
E: protects membrane lipids
2
Q
what are peroxides
A
highly reactive oxygen species that can damage membranes and other biomoleucles
3
Q
peroxide detoxification
A
by the glutathione peroxidase catalysed reaction
uses reduced glutathione
creates an alcohol, water and oxidised glutathione
4
Q
what are superoxides
A
O2-
5
Q
super oxides detoxified by
A
the enzyme SOD
converts the superoxide into O2 and itself is reduced
creates H202
6
Q
H202 breakdown
A
by catalase into oxygen and water
