Reactive lesions of the oral mucosa Flashcards
What are the histological layers and compartments
(TOP)
Stratum corneum
Granulosum
Spinosum
Basale
Lamina Propria
(BOTTOM)
What different reactions of the oral epithelium can you get
keratosis
-nonkeratinised site (parakeratosis)
acanthosis
-hyperplasia of stratum spinosum
elongated rete ridges
-hyperplasia of basal cells
atrophy
-reduction in viable layers
erosion
-partial thickness loss
ulceration
-full thickness loss with fibrin on surface
oedema
-intracellular
-intercellular (spongiosis)
blister - vesicle or bulla
What is meant by dysplasia
Disordered maturation (growth) in a tissue
What is meant by atypia
Describes changes in cells
What is a epulide
Soft tissue swellings on the gingiva only
Reaction to chronic inflammation/chronic trauma that can reoccur after removal if stimulus persists
What is a pyogenic granuloma and its other names
Granulation tissue on any mucosal site that is in response to trauma
Other names:
gingiva– aka vascular epulis (most frequent site)
gingiva, during pregnancy-
pregnancy epulis
Occasionally other types of soft tissue swellings may present on the gingiva such as odontogenic tumours and cysts, What does the word peripheral mean in regards to describing the lesions
Used to say the lesion originated on the gingiva and from the bone
Why are giant cell lesions giant and what causes them
Giant because of the Fused macrophages
Causes
-unphagocytosable material
-local chronic irritation
-infective agents e.g.TB bacillus
-hormonal stimulation of cells
-Autoimmune sarcoidosi
With giant cell lesions what is it important to exclude
systemic disease:
-raised parathyroid hormone
-low vitamin D in diet
-malabsorption
-renal disease
What drugs induce fibrous overgrowth
Anti-hypertensives
-Calcium Channel Blockers
Anti-epileptics
-Phenytoin
Immunosuppressants
-Ciclosporin
What is in the histology of papillary hyperplasia of palate
Pseudo- epitheliomatous hyperplasia
