reactions im not 100% about Flashcards
How do you go from a primary alcohol to a haloalkane?
Reaction with hydrogen halides that are formed in place under reflux
E.g forming Hbr by reacting H2SO4 and NaBr.
NaHSO4 and H2O will also form as side products.
How do you go from a haloalkane to an amine?
By reacting with an excess of NH3 and ethanol will produce an amine.
You can do the same with a primary amine instead of NH3 to produce a secondary amine
How do you go from a haloalkane to a nitrile?
Heated under reflux with NaCN in ethanol and not water as H2O would substitute a OH group
The CN- will replace the halogen
How do you go from a nitrile to a carboxylic acid?
By acid hydrolysis you will produce a carboxylic acid and NH4Cl
How do you get from an acyl chloride to an amide?
React with ammonia or primary amines to produce different levels of amides.
How do you go from an acyl chloride to a carboxylic acid and vise versa?
Acyl chloride to carboxylic acid= Adding water which will also produce HCL
Carboxylic acid to acyl chloride: Reaction with SOCl2 which will also produce SO2 and HCL that will evolve away
How do you go from aldehyde to hydroxynitrile?
React with NaCN/H+ via nucleophilic addition
How do you go from a nitrile to amine?
Reduced by using H2 and a nickel catalyst which acts as a reducing agent