reactions Flashcards
1
Q
Reagents to open an epoxide
A
1) NaOH
2) H2O
2
Q
Reagents to open an epoxide beside hydroxide
A
1) NaOR
2) H2O
3
Q
Which part of the epoxide is more vulnerable to being open? (more or less substituated)
A
less substituated side.
4
Q
Treatment of H20 is needed when strong bases are present because
A
even a weak acid would ruin things like LiAlH4 or CH3MgBr
5
Q
Epoxide treatment with HX causes opening at the (more or less substituated carbon?)
A
more, which is the opposite of the strong bases
SN2 doesn’t usually occur at tertiary substrate, but this is an exception
6
Q
NaCN
A
is a nucleophile
7
Q
NaSH
A
is a nucleophile
8
Q
LiAlH4
A
is a nucleophile
9
Q
Under acidic conditions, things like -OR groups are added to the (more less substituated carbon
A
more
