Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Hema > RBCs And WBCs > Flashcards

RBCs And WBCs Flashcards

1
Q

Predominant WBC in adults

A

Neutrophils

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Neutrophils and monocytes are direct descendants of a common progenitor, known as?

A

GMP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Majors stimulatory cytokine for neutrophil production 

A

G-CSF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the half-life of neutrophils in the blood?

A

7 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Able to trap and kill gram-positive and gram-negative bacteria, as well as fungi?

A

NETs (Neutrophil Extracellular Traps)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

An enzyme that exhibits bactericidal, fungicidal and viricidal properties

A

MPO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Lysozyme is also known as

A

Muramidase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

And iron-binding protein that competes with bacteria for iron

A

Lactoferrin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

The most specific cytokines for eosinophil lineage

A

IL-5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Circuiting half life of eosinophils

A

18 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Survival time of eosinophils in human tissues ranges from

A

2 to 5 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

This happens when extracellular intact granules are deposited during cell lysis

A

Cytolisis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

A method of eosinophil degranulation, where secretary vehicles removes specific proteins from the secondary granules. These vesicles then travel to the plasma membrane and infused to empty specific proteins into the extracellular space. 

A

Piecemeal degranulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Color of Charcot-Leyden crystal in: Hematoxylin, Eosin and Trichrome stain

A

Hematoxylin- Black
Eosin- Red
Trichrome stain- Purplish-red

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Life span of basophils

A

60 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

A dye that can bind with acid mucopolysaccharides in blood cells to form metachromatic complexes

A

Toluidine blue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Histochemically defined as a reaction product color that is considerably different from the color of the dye itself

A

Metachromasia

18
Q

An enzyme needed to breakdown lipids

A

Sphingomyelinase

19
Q

Rare autosomal recessive
Deficiency of sphingomyelinase
Splenomegaly and hepatomegaly
Characteristic cells: Pick’s cells
A MAC whose cytoplasm is swollen by many small lipid droplets

A

Niemann-Pick Disease

20
Q

Niemann-Pick Disease which is fatal by 3 yrs of age, is most commonly seen in?

A

Ashkenazi Jews

21
Q

Most common lipidoses, Aut. Recess.; defect OR deficiency in the catabolic enzyme B-glucerebrosidase

A

Gaucher Disease

22
Q

Appearance of Gaucher cell

A

Crumpled tissue paper or onion skin

23
Q

A rare hereditary condition characterized by normal granulocyte production. Nevertheless, there is impaired released into the blood leading to neutropenia. 

A

Myelokathexis

24
Q

Most common genetic disorder of WBCs; it is the failure of the neutrophil nucleus the segment
“Pince-nez” or “spectacle” form neutrophil nucleus
Autosomal Dominant

A

Pelger-Huet Anomaly aka True/Congenital PHA

25
Q

This is an inner nuclear membrane protein; place a major role in leukocyte nuclear shape changes that occur during normal maturation

A

Lamin beta-receptor 

26
Q

True or false. There is normal granulation in through PHA 

A

True

27
Q

ME ratio of leukemia

A

10:1

28
Q

Type of anemia usually seen in cases of acute leukemia

A

Normo normo

29
Q

Most common form of childhood leukemia

A

Acute Lymphocytic Leukemia

30
Q

Peroxidase stain rules out what type of leukemia?

A

Acute Lymphocytic Leukemia (ALL)

31
Q

Most sensitive stain for granulocytic precursors

A

Sudan Black B (SBB)

32
Q

Basic unit of Radiation

A

Photon

33
Q

Part of the platelet that ultimately dileanates individual platelets during thrombocytopoeisis

A

Demarcation System

34
Q

An unique phospholipid found in the inner cytoplasmic layer of the platelets which flips to the outer surface upon activation, and is the charge phospholipid surface on which 2 coagulation pathway complexes assemble 

A

Phosphatidylserine

35
Q

What are the two coagulation passed away complexes that assembles at the phosphatidylserine surface?

A

TENASE complex and PROTHROMBINASE complex 

36
Q

It is the cellular ultrastructural component, unique only to the platelets

A

Glycocalyx

37
Q

A molecule that binds to another molecule (especially the reference to a small molecule that specifically binds to the larger molecule)

A

Ligand

38
Q

What does CAM stand for?

A

Cell Adhesion Molecule

39
Q

What are the Ligands of GPIa/IIa? 

A

Collagen
Vitronectin
Laminin
Fibronectin

40
Q

Deficiency of Factor V

A

Owren’s Disease/ Parahemophilia

41
Q

First coagulation factor to be affected by warfarin therapy

A

Factor VII

Hema (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions