RBC, WBC, and Anemia Flashcards
sensitivity rules __ disease
out
specificity rules __ disease
in
hb equation
hb = rbc x 3
hematocrit equation
hct = hb x 3
or
hct = rbc x 9
rbcs are indirect measure of what
hemoglobin
hematocrit is indirect measure of what
rbcs in volume of blood
what tells you average size of rbc
MCV
what tells you quantity of hemoglobin in rbc
MCH
what tells you concentration or color of rbc
MCHC
increase in RDW suggests what
what conditions
increase in different types of cell sizes
factor deficiency, homozygous globinpathy
normal RDW suggests what conditions
thalassemia minor
heterozygous globinpathy
chronic disease anemia
what is a spherocyte
type of microcyte
round and lacks center clear area
what are polychromatophile RBCs
reticulocytes
immature RBCs
what is rouleaux
rbcs partially adhering to each other like stack of coins
what is anemia defined as
decrease in hemoglobin concentration
may result from loss of RBCs which contain hb
what are the causes of pseudoanemia
overhydration fluid retention pregnancy athletics hypoalbuminemia lab error posture
what are causes of anemia
hemorrhage bone marrow failure renal disease dietary deficit hemolytic disease
anemia is classified by what
cell morphology
- macrocytic, micro, normo
- hypochromic, normo
pathogenesis
- factor deficiency
- production deficit
- depletion
what are the steps to determine if patient is anemic
ask question - are they anemia
morphology classification
pathogenesis
factor deficiency results from what
lack of raw materials necessary for hematopoesis
what are factors necessary for hb synthesis
iron
b12
folic acid
pyridioxine
microcytosis results from hb molecule lacking __ or __
iron - IDA
pyridoxine - sideroblastic anemia
most common cause of microcytosis
IDA
MCV and MCHC decrease
IDA