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MLT 108 > RBC Morphology > Flashcards

RBC Morphology Flashcards

1
Q

Anisocytosis

A

Abnormal variation of RBC size or volume

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2
Q

Anisocytosis related disorders

A

Hemolytic anemia
Megaloblastic anemia
Fe deficiency anemias

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3
Q

Macrocyte

A

Large RBCs; > 8 mm diameter; > 100 fL

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4
Q

Macrocyte related disorders

A

Megaloblastic anemia
Myelodysplastic syndrome
Chronic liver disease
BM failure
Reticulocytosis

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5
Q

Microcyte

A

Small RBCs; <6 um; MCV < 8 fL

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6
Q

Microcyte related disorders

A

Fe deficiency anemia
Anemia of chronic inflammation
Sideroblastic anemia
Thalassemia / Hb E disease and trait

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7
Q

Poikilocytosis

A

Abnormal variation in RBC shape.

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8
Q

Poikilocytosis related disorder

A

Severe anemia

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9
Q

Spherocyte

A

Elliptical or oval shaped RBC

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10
Q

Elliptocyte related disorders

A

Hereditary elliptocytosis/ovalocytosis
Fe deficiency anemia
Thalassemia
Myelophthisic anemias

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11
Q

Stomatocyte

A

RBC central pallor resembles a mouth; slit-like area

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12
Q

Stomatocyte related disorders

A

Hereditary or acquired stomatocytosis (acquired: liver disease, alcoholism)
Rh deficiency syndrome
Artifact

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13
Q

Codocyte

A

RBC resembling a target
Hgb conc in the center and around the periphery

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14
Q

Codocyte related disorders

A

Liver disease
Hemoglobinopathies
Thalassemia

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15
Q

Keratocyte

A

RBC fragment that resembles a helmet

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16
Q

Keratocyte related disorders

A

Micro or macroangiopathic hemolytic anemia
Extensive burns

17
Q

Acanthocyte

A

Small, dense RBCs w/uneven spikes on the surface
Spikes vary in length and are irregularly spaced
AKA Spur Cells

18
Q

Acanthocyte related disorders

A

Severe liver disease
Spur cell anemia
Neuroacanthocytosis
Abetalipoproteinemia
McLeod syndrome

19
Q

Echinocyte

A

RBCs with even spikes on their surface
Spikes are blunt or pointed and evenly spaced
Typically present on all fields of a blood film
AKA Burr Cells

20
Q

Echinocyte related disorders

A

Uremia
Pyruvate kinase deficiency

21
Q

Dacrocyte

A

Teardrop or pear shaped RBC
Single pointed extension

22
Q

Dacrocyte related disorders

A

Primary myelofibrosis
Myelophthisic anemia
Thalassemia
Megaloblastic anemia

23
Q

Schistocyte

A

RBC fragments
Rupture in peripheral circulation

24
Q

Schistocyte related disorders

A

Micro or macroangiopathic hemolytic anemia
Extensive burns

25
Q

Sickle cell

A

Thin, dense, elongated RBCs that taper to a point or curve at the ends.

26
Q

Sickle cell related disorders

A

Sickle cell anemia
Sickle cell beta thalassemia

27
Q

Rouleaux

A

Stacking of RBCs
Stack of coins

28
Q

Rouleaux related disorders

A

Hyperfibrinogenemia
Hyperglobulinemia

MLT 108 (4 decks)

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