RATs lecture quiz #1 DISEASES

Question 1

Pneumonia

Answer 1

Path: Bacterial
Cause: Mycoplasma pulmonis; Klebsiella pneumoniae
Sympt:teeth chatt, labored resp, weight loss, conjuctivitis
Treat:ampicillin, oxytetracycline

Question 2

Helicobacter spp. Infection

Answer 2

Path: Bacterial Cause: Heliobacter
bilis; Heliobacter hepaticus
Sympt: Clin signs mostly not seen until liver disease end stage, but IBD, rectal prolapse, chronic hep
Treat: Transfer neos on first day of life, microisolation, multi-antibiotic regimen

Question 3

Tysser’s Disease

Answer 3

Path: bacteria
Cause agent: Clostridium piliforme
Sympt: dehydration, anorexia. Gross lesions on liver necropsy
Treat: prevention most effect, but high doses of tetracycline for 4-5 days rept’d favorable

Question 4

Colonic Hyperplasia Disease

Answer 4

Path: Bacterial
Cause: Citrobacter rodentium
Sympt:High infant mortality! entetcolitis, retarded growth, occ. rectal prolapse,mostly gross finding at nec’r of thickening of distal colon.
Treat: neomycin, tetracycline, sulfamethazine

Question 5

Hyperkeratosis-Associated Coryneform (HAC)

Answer 5

Path:Baterial
Cause: Corynebacterium bovis
Symp: hyperkeratotic derm in nude mice and neonatal SCID; dry white flaky skin, pruritis that lasts 1 wk
Treat: no known. euthanize to prev spread

Question 6

Parvoviruses

Answer 6

Path: Viral
Cause:MPV 1, mouse minute virus (MMV)
Sympt: runting & cerebral hypoplasia in neo’s, MPV causes immune system problems
Treat: depop of infected mice and/or cesarean rederivation or embryo transfer of valuable mice. Chem disinfectant like Hyd. Peroxide

Question 7

Sendai Virus

Answer 7

Path: Viral
Cause: parainfluenza 1 virus
Sympt: in immunosuppressed mice, hunched, erect coat, dyspnea, crusty eyes, chattering
Treat: burnout, barrier housing to prevent.

Question 8

Murine Retroviral Infection

Answer 8

Path: provirus
Cause: MuLeukemia Virus
Sympt:tumors, leukemia
Treat: Cannot be treated

Question 9

Mouse Hepatitis Virus

Answer 9

Path: Coronavirus
Cause: MHV
Sympt: usually subclin, but may runing, no milk spots, encephalitis
Treat: in healthy mice, secession of breeding to allow clearing of virus

Question 10

Epizootic diarrhea of infant mice

Answer 10

Path:rotavirus
Cause:EDIM
Sympt: soft yellow feces
Treat: None but supportive care

Question 11

Lymphocytic Choriomeningitis

Answer 11

Path: virus
Cause: LCMV
Sympt: Latent -Asymptomac in mice. May cause flu like in humans

Question 12

Murine Norovirus

Answer 12

Path: virus
Cause: Murine calicivirus
sympt:can be asymptom
Treat: no known. bleach 1:10 to kill

Question 13

Mites

Answer 13

path: parasitic
Cause: myobia musculi, radfordia affinis, myocoptes musculinus
Sympt: heavy infest dermatitis, alopecia, greasy hair, self trauma
Treat: Ivermectin, permethrin dusts/soaked balls

Question 14

Pinworms

Answer 14

Syphacia obvelata, Aspiculuris tetraptera
Symp:asympt, but poor hair coat, mucoid enteritis
Treat: Ivermectin, Fenbendazole

Question 15

Lice

Answer 15

Cause: Polyplax serrata
Sympt. Skin irrit, anemia
Treat: Ivermectin, permethrin

Question 16

Tapeworm

Answer 16

Rodentolepis nana, Hymenolepis diminuta
Asymptom or ova
Treat:thiabendazole

Question 17

Flagellates

Answer 17

Giardia muris
Sympt: diarehhea or asymptomatic
Treat:metronidazole controls outbreaks, but doesn’t eliminate

Question 18

Ulcerative Dermatitis

Answer 18

Path: Genetic
Clin signs severe puritis with excoriation, ulceration and loss of skin most common dorsal cervical
Treat: Antibiotics, cortosteroids