Rate Limiting Steps Flashcards

1
Q

Pyrimidine

A

aspartate transcarbamoylase

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2
Q

Purine

A

glutamine PRPP aminotransferase

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3
Q

Glycolysis

A

phosphofructokinase 1

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4
Q

Gluconeogenesis

A

pyruvate carboxylase

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5
Q

FA synthesis

A

acetyl coA carboxylase

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6
Q

FA oxidation

A

carnitine acyltransferase 1

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7
Q

TCA cycle

A

isocitrate dehydrogenase

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8
Q

Ketogenesis

A

HMGCoA synthase

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9
Q

Cholesterol Synthesis

A

HMGCoA reductase

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10
Q

Urea

A

carbamoyl phosphate synthase 1

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11
Q

Glycogen synthesis

A

glycogen synthase

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12
Q

Glycogenolysis

A

glycogen phosphorylase

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13
Q

Heme

A

ALA synthase

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14
Q

Aspartate transcarbamoylase inhibited by:

A

CTP

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15
Q

Hexokinase inhibited by:

A

Glucose-6-phosphate

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16
Q

Phosphofructokinase activated by:

A

fructose 2,6 diphosphate, AMP, ADP

17
Q

Phosphofructokinase inhibited by:

A

ATP, Citrate

18
Q

Pyruvate kinase activated by:

A

ATP

19
Q

Protein kinase activated by:

A

epinephrine

20
Q

Phosphorylase b kinase activated by:

A

glucose-6-phosphate, AMP

21
Q

Phosphorylase b kinase & phosphorylase phosphatase inhibited by:

A

Calcium

22
Q

Pyruvate carboxylase activated by:

A

acetyl CoA

23
Q

Pyruvate carboxylase inhibited by:

A

ADP

24
Q

AMP inihibits:

A

fructose-1,6-biphosphatase

25
Q

AMP activates:

A

pyruvate dehydrogenase

26
Q

Pyruvate dehydrogenase inhibited by:

A

ATP, NADH, Acetyl CoA

27
Q

ADP activates:

A

isocitrate dehydrogenase

28
Q

Fructose-1,6-biphosphatase activated by:

A

AMP

29
Q

Glycogen synthetase activated by:

A

glucose-6-phosphate